I. Genetic and environmental effects on preimplantation development of mouse embryo in vitro

Kazuaki Nonaka, Y. Sasaki, T. Matsumoto, K. I. Yanagita, Y. Watanabe, E. Nagata, M. Nakata

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

To examine the degree of the relative contribution of genetic and environmental effects to preimplantation development of mouse embryo in vitro, two-cell stage embryos collected from oviducts of five strains of inbred mice (DDD/Qdj, C3H/Qdj, C57BL/6J Sea, DBA/1J Sea, and BALB/C Sea) were cultivated up to the stage of expanded blasytocyst for 72 hr. Both fertility and survival rates were calculated in each recipient and also in each strain. A Student-Newman-Keuls test for both rates showed a significant inter-strain difference and an analysis of variance done to estimate the relative importance of genetic and environmental effects on the preimplantation development of embryo showed a low degree of genetic determination for both rates. It was thus possible to conclude that the environmental effect played a more important role on preimplantation development of mouse embryo in vitro.

Original languageEnglish
Pages (from-to)202-205
Number of pages4
JournalJournal of Craniofacial Genetics and Developmental Biology
Volume13
Issue number3
Publication statusPublished - Jan 1 1993

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology

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