Identification of sixteen new galactocerebrosides from the starfish protoreaster nodosus

Ke Pan, Masanori Inagaki, Nagisa Ohno, Chiaki Tanaka, Ryuichi Higuchi, Tomofumi Miyamoto

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Twenty-one galactocerebrosides (1-21), including sixteen new compounds (3-7, 9-17, 19, 21), were identified from a cerebroside molecular species obtained from the chloroform/methanol extract of pyloric caeca dissected from the starfish Protoreaster nodosus. The structures of these galactocerebrosides were determined on the basis of chemical and spectroscopic evidences. Especially, one-pot GC-MS analysis following methanolysis and periodate oxidation of these galactocerebrosides gave efficient structural information of ceramide moiety rapidly in minute amounts.

Original languageEnglish
Pages (from-to)470-474
Number of pages5
JournalChemical and Pharmaceutical Bulletin
Volume58
Issue number4
DOIs
Publication statusPublished - Apr 1 2010

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Starfish
Galactosylceramides
Cerebrosides
Ceramides
Chloroform
Methanol
Oxidation

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

Cite this

Identification of sixteen new galactocerebrosides from the starfish protoreaster nodosus. / Pan, Ke; Inagaki, Masanori; Ohno, Nagisa; Tanaka, Chiaki; Higuchi, Ryuichi; Miyamoto, Tomofumi.

In: Chemical and Pharmaceutical Bulletin, Vol. 58, No. 4, 01.04.2010, p. 470-474.

Research output: Contribution to journalArticle

Pan, Ke ; Inagaki, Masanori ; Ohno, Nagisa ; Tanaka, Chiaki ; Higuchi, Ryuichi ; Miyamoto, Tomofumi. / Identification of sixteen new galactocerebrosides from the starfish protoreaster nodosus. In: Chemical and Pharmaceutical Bulletin. 2010 ; Vol. 58, No. 4. pp. 470-474.
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