Identification of the lantibiotic nisin q, a new natural nisin variant produced by lactococcus lactis 61-14 isolated from a river in japan

Takeshi Zendo, Masanori Fukao, Kyoko Ueda, Tomoko Higuchi, Jiro Nakayama, Kenji Sonomoto

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

Lactococcus lactis 61-14 isolated from river water produced a bacteriocin active against a wide range of Gram-positive bacteria. N-terminal amino acid sequencing, mass spectral analysis of the purified bacteriocin, and genetic analysis using nisin-specific primers showed that the bacteriocin was a new natural nisin variant, termed nisin Q. Nisin Q and nisin A differ in four amino acids in the mature peptide and two in the leader sequence.

Original languageEnglish
Pages (from-to)1616-1619
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume67
Issue number7
DOIs
Publication statusPublished - Jan 1 2003

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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