Identification of the nukacin KQU-131, a new type-A(II) lantibiotic produced by Staphylococcus hominis KQU-131 isolated from Thai fermented fish product (Pla-ra)

Pongtep Wilaipun, Takeshi Zendo, Ken Ichi Okuda, Jiro Nakayama, Kenji Sonomoto

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Staphylococcus hominis KQU-131, isolated from Thai fermented marine fish, produces a heat stable bacteriocin. Structural and genetic analysis indicated that the bacteriocin is a variant of nukacin ISK-1, a type-A(II) lantibiotic, and we termed the bacteriocin nukacin KQU-131. There were three different amino acid residues between nukacin ISK-1 and nukacin KQU-131, one residue in the leader peptide and the other two in the mature peptide.

Original languageEnglish
Pages (from-to)2232-2235
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume72
Issue number8
DOIs
Publication statusPublished - 2008

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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