Abstract
We continuously observed successive pairs of R-R intervals during atrial fibrillation and hypothesized that the shortest R-R interval for a given preceding R-R interval in a pair represents the functional refractory period of the atrioventricular node at that preceding interval. To test this hypothesis we simulated atrial fibrillation in 28 isolated cross-perfused canine hearts and obtained an R-R interval scatterplot by plotting the R-R intervals as a function of the immediately preceding R-R interval. This scatterplot enabled us to detect a series of the shortest R-R intervals for a wide range of preceding R-R intervals, and this allowed us to estimate the rate-dependent functional refractory period of the atrioventricular node in simulated atrial fibrillation. The estimated functional refractory periods correlated well with those measured by the conventional method (r = 0.93). We conclude that the proposed method makes it possible to estimate the rate-dependent functional refractory periods of the atrioventricular node in atrial fibrillation.
| Original language | English |
|---|---|
| Pages (from-to) | 820-826 |
| Number of pages | 7 |
| Journal | American heart journal |
| Volume | 121 |
| Issue number | 3 PART 1 |
| DOIs | |
| Publication status | Published - Jan 1 1991 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
Cite this
Identification of the rate-dependent functional refractory period of the atrioventricular node in simulated atrial fibrillation. / Chishaki, Akiko; Sunagawa, Kenji; Hayashida, Kiyoshi; Sugimachi, Masaru; Nakamura, Motoomi.
In: American heart journal, Vol. 121, No. 3 PART 1, 01.01.1991, p. 820-826.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Identification of the rate-dependent functional refractory period of the atrioventricular node in simulated atrial fibrillation
AU - Chishaki, Akiko
AU - Sunagawa, Kenji
AU - Hayashida, Kiyoshi
AU - Sugimachi, Masaru
AU - Nakamura, Motoomi
PY - 1991/1/1
Y1 - 1991/1/1
N2 - We continuously observed successive pairs of R-R intervals during atrial fibrillation and hypothesized that the shortest R-R interval for a given preceding R-R interval in a pair represents the functional refractory period of the atrioventricular node at that preceding interval. To test this hypothesis we simulated atrial fibrillation in 28 isolated cross-perfused canine hearts and obtained an R-R interval scatterplot by plotting the R-R intervals as a function of the immediately preceding R-R interval. This scatterplot enabled us to detect a series of the shortest R-R intervals for a wide range of preceding R-R intervals, and this allowed us to estimate the rate-dependent functional refractory period of the atrioventricular node in simulated atrial fibrillation. The estimated functional refractory periods correlated well with those measured by the conventional method (r = 0.93). We conclude that the proposed method makes it possible to estimate the rate-dependent functional refractory periods of the atrioventricular node in atrial fibrillation.
AB - We continuously observed successive pairs of R-R intervals during atrial fibrillation and hypothesized that the shortest R-R interval for a given preceding R-R interval in a pair represents the functional refractory period of the atrioventricular node at that preceding interval. To test this hypothesis we simulated atrial fibrillation in 28 isolated cross-perfused canine hearts and obtained an R-R interval scatterplot by plotting the R-R intervals as a function of the immediately preceding R-R interval. This scatterplot enabled us to detect a series of the shortest R-R intervals for a wide range of preceding R-R intervals, and this allowed us to estimate the rate-dependent functional refractory period of the atrioventricular node in simulated atrial fibrillation. The estimated functional refractory periods correlated well with those measured by the conventional method (r = 0.93). We conclude that the proposed method makes it possible to estimate the rate-dependent functional refractory periods of the atrioventricular node in atrial fibrillation.
UR - http://www.scopus.com/inward/record.url?scp=0025978074&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025978074&partnerID=8YFLogxK
U2 - 10.1016/0002-8703(91)90194-M
DO - 10.1016/0002-8703(91)90194-M
M3 - Article
C2 - 2000749
AN - SCOPUS:0025978074
VL - 121
SP - 820
EP - 826
JO - American Heart Journal
JF - American Heart Journal
SN - 0002-8703
IS - 3 PART 1
ER -