TY - JOUR
T1 - Idiopathic cortical myoclonus restricted to the lower limbs
T2 - Correlation between MEPs and 99mTc-ECD single photon emission computed tomography activation study
AU - Tanaka, Kimihiro
AU - Suga, Ri E.
AU - Yamada, Takeshi
AU - Tobimatsu, Shozo
AU - Sasaki, Masayuki
AU - Kuwabara, Yasuo
AU - Furuya, Hirokazu
AU - Kobayashi, Takuro
AU - Kira, Jun Ichi
PY - 1999/2/1
Y1 - 1999/2/1
N2 - We report a 63-year-old woman with cortical reflex myoclonus restricted to the bilateral lower limbs. Somatosensory evoked cortical potentials to posterior tibial nerve stimulation were enlarged with C-responses. Jerk- locked back averaging of the EEG identified a cortical spike related to myoclonic jerks. Motor evoked potentials recorded from the abductor hallucis muscle showed an exaggerated late response. These findings suggest hyperexcitability of the sensorimotor cortex. 99mTc-ECD single photon emission computed tomography (SPECT) after stimulation of the posterior tibial nerve showed increased perfusion in the contralateral peri-Rolandic area which corresponded to the hyperexcitable region. ASPECT activation study as well as MEPs therefore can be employed to determine the hyperexcitable region in cortical myoclonus.
AB - We report a 63-year-old woman with cortical reflex myoclonus restricted to the bilateral lower limbs. Somatosensory evoked cortical potentials to posterior tibial nerve stimulation were enlarged with C-responses. Jerk- locked back averaging of the EEG identified a cortical spike related to myoclonic jerks. Motor evoked potentials recorded from the abductor hallucis muscle showed an exaggerated late response. These findings suggest hyperexcitability of the sensorimotor cortex. 99mTc-ECD single photon emission computed tomography (SPECT) after stimulation of the posterior tibial nerve showed increased perfusion in the contralateral peri-Rolandic area which corresponded to the hyperexcitable region. ASPECT activation study as well as MEPs therefore can be employed to determine the hyperexcitable region in cortical myoclonus.
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U2 - 10.1016/S0022-510X(98)00326-8
DO - 10.1016/S0022-510X(98)00326-8
M3 - Article
C2 - 10223412
AN - SCOPUS:0033081232
VL - 163
SP - 58
EP - 60
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
SN - 0022-510X
IS - 1
ER -