Image sensor with hybrid emission filter for in vivo fluorescent imaging

Kiyotaka Sasagawa; Erus Rustami; Yasumi Ohta; Makito Haruta; Hironari Takehara; Hiroyuki Tashiro; Jun Ohta

doi:10.1002/ecj.12313

Image sensor with hybrid emission filter for in vivo fluorescent imaging

Kiyotaka Sasagawa, Erus Rustami, Yasumi Ohta, Makito Haruta, Hironari Takehara, Hiroyuki Tashiro, Jun Ohta

Division of Medical Technology

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

In this paper, we report a method of fabricating an implantable image sensor equipped a bandpass hybrid filter for highly sensitive fluorescence observation. A hybrid filter that combines an interference filter and an absorption filter enables a high excitation light removal performance in an implantable image sensor that does not use a lens. In this study, a thin hybrid filter was successfully mounted on the image sensor using the transfer method by using a laser lift-off technique. The transferred filter has no crack. It was demonstrated that the prototype device exhibited high excitation light removal performance and was able to acquire a fluorescent image with high contrast.

Original language	English
Article number	e12313
Journal	Electronics and Communications in Japan
Volume	104
Issue number	2
DOIs	https://doi.org/10.1002/ecj.12313
Publication status	Published - Jun 2021

All Science Journal Classification (ASJC) codes

Signal Processing
Physics and Astronomy(all)
Computer Networks and Communications
Electrical and Electronic Engineering
Applied Mathematics

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10.1002/ecj.12313

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title = "Image sensor with hybrid emission filter for in vivo fluorescent imaging",

abstract = "In this paper, we report a method of fabricating an implantable image sensor equipped a bandpass hybrid filter for highly sensitive fluorescence observation. A hybrid filter that combines an interference filter and an absorption filter enables a high excitation light removal performance in an implantable image sensor that does not use a lens. In this study, a thin hybrid filter was successfully mounted on the image sensor using the transfer method by using a laser lift-off technique. The transferred filter has no crack. It was demonstrated that the prototype device exhibited high excitation light removal performance and was able to acquire a fluorescent image with high contrast.",

author = "Kiyotaka Sasagawa and Erus Rustami and Yasumi Ohta and Makito Haruta and Hironari Takehara and Hiroyuki Tashiro and Jun Ohta",

note = "Funding Information: This study was in part assisted by JST‐CREST (JPMJCR1654), JSPS Grant‐in‐Aid for Scientific Research (18H03519, 18H03780), and grant‐in‐aid by The Futaba Foundation. In addition, the study received cooperation from Cadence Design Systems, Japan and Mentor Graphics via Systems Design Lab, The University of Tokyo. Funding Information: This study was in part assisted by JST-CREST (JPMJCR1654), JSPS Grant-in-Aid for Scientific Research (18H03519, 18H03780), and grant-in-aid by The Futaba Foundation. In addition, the study received cooperation from Cadence Design Systems, Japan and Mentor Graphics via Systems Design Lab, The University of Tokyo. Publisher Copyright: {\textcopyright} 2021 Wiley Periodicals LLC",

year = "2021",

month = jun,

doi = "10.1002/ecj.12313",

language = "English",

volume = "104",

journal = "Electronics and Communications in Japan",

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AU - Sasagawa, Kiyotaka

AU - Rustami, Erus

AU - Ohta, Yasumi

AU - Haruta, Makito

AU - Takehara, Hironari

AU - Tashiro, Hiroyuki

AU - Ohta, Jun

N1 - Funding Information: This study was in part assisted by JST‐CREST (JPMJCR1654), JSPS Grant‐in‐Aid for Scientific Research (18H03519, 18H03780), and grant‐in‐aid by The Futaba Foundation. In addition, the study received cooperation from Cadence Design Systems, Japan and Mentor Graphics via Systems Design Lab, The University of Tokyo. Funding Information: This study was in part assisted by JST-CREST (JPMJCR1654), JSPS Grant-in-Aid for Scientific Research (18H03519, 18H03780), and grant-in-aid by The Futaba Foundation. In addition, the study received cooperation from Cadence Design Systems, Japan and Mentor Graphics via Systems Design Lab, The University of Tokyo. Publisher Copyright: © 2021 Wiley Periodicals LLC

PY - 2021/6

Y1 - 2021/6

N2 - In this paper, we report a method of fabricating an implantable image sensor equipped a bandpass hybrid filter for highly sensitive fluorescence observation. A hybrid filter that combines an interference filter and an absorption filter enables a high excitation light removal performance in an implantable image sensor that does not use a lens. In this study, a thin hybrid filter was successfully mounted on the image sensor using the transfer method by using a laser lift-off technique. The transferred filter has no crack. It was demonstrated that the prototype device exhibited high excitation light removal performance and was able to acquire a fluorescent image with high contrast.

AB - In this paper, we report a method of fabricating an implantable image sensor equipped a bandpass hybrid filter for highly sensitive fluorescence observation. A hybrid filter that combines an interference filter and an absorption filter enables a high excitation light removal performance in an implantable image sensor that does not use a lens. In this study, a thin hybrid filter was successfully mounted on the image sensor using the transfer method by using a laser lift-off technique. The transferred filter has no crack. It was demonstrated that the prototype device exhibited high excitation light removal performance and was able to acquire a fluorescent image with high contrast.

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JO - Electronics and Communications in Japan

JF - Electronics and Communications in Japan

IS - 2

M1 - e12313

ER -

Image sensor with hybrid emission filter for in vivo fluorescent imaging

Abstract

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