Imaging mass spectrometry of intravenously injected gold nanorods in mice

Masanori Fujii, Naotoshi Nakashima, Takuro Niidome, Yasuro Niidome

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Laser-induced desorption and ionization (LDI) of gold ions (Aun +: n = 13) were observed from gold nanorods in a liver tissue section (thickness: 10 -m). Larger amounts of gold nanorods produced stronger mass signals. Organic molecules in the tissue were not detected and did not inhibit the LDI processes of the gold nanorods in the tissue. Because of the selective LDI processes of the gold nanorods, the distribution of gold in the liver was successfully determined by imaging mass spectrometry.

Original languageEnglish
Pages (from-to)131-133
Number of pages3
JournalChemistry Letters
Volume43
Issue number1
DOIs
Publication statusPublished - 2014

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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