Imaging mass spectrometry of intravenously injected gold nanorods in mice

Masanori Fujii; Naotoshi Nakashima; Takuro Niidome; Yasuro Niidome

doi:10.1246/cl.130864

Imaging mass spectrometry of intravenously injected gold nanorods in mice

Masanori Fujii, Naotoshi Nakashima, Takuro Niidome, Yasuro Niidome

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Laser-induced desorption and ionization (LDI) of gold ions (Aun +: n = 13) were observed from gold nanorods in a liver tissue section (thickness: 10 -m). Larger amounts of gold nanorods produced stronger mass signals. Organic molecules in the tissue were not detected and did not inhibit the LDI processes of the gold nanorods in the tissue. Because of the selective LDI processes of the gold nanorods, the distribution of gold in the liver was successfully determined by imaging mass spectrometry.

Original language	English
Pages (from-to)	131-133
Number of pages	3
Journal	Chemistry Letters
Volume	43
Issue number	1
DOIs	https://doi.org/10.1246/cl.130864
Publication status	Published - 2014

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1246/cl.130864

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abstract = "Laser-induced desorption and ionization (LDI) of gold ions (Aun +: n = 13) were observed from gold nanorods in a liver tissue section (thickness: 10 -m). Larger amounts of gold nanorods produced stronger mass signals. Organic molecules in the tissue were not detected and did not inhibit the LDI processes of the gold nanorods in the tissue. Because of the selective LDI processes of the gold nanorods, the distribution of gold in the liver was successfully determined by imaging mass spectrometry.",

author = "Masanori Fujii and Naotoshi Nakashima and Takuro Niidome and Yasuro Niidome",

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journal = "Chemistry Letters",

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AU - Fujii, Masanori

AU - Nakashima, Naotoshi

AU - Niidome, Takuro

AU - Niidome, Yasuro

PY - 2014

Y1 - 2014

N2 - Laser-induced desorption and ionization (LDI) of gold ions (Aun +: n = 13) were observed from gold nanorods in a liver tissue section (thickness: 10 -m). Larger amounts of gold nanorods produced stronger mass signals. Organic molecules in the tissue were not detected and did not inhibit the LDI processes of the gold nanorods in the tissue. Because of the selective LDI processes of the gold nanorods, the distribution of gold in the liver was successfully determined by imaging mass spectrometry.

AB - Laser-induced desorption and ionization (LDI) of gold ions (Aun +: n = 13) were observed from gold nanorods in a liver tissue section (thickness: 10 -m). Larger amounts of gold nanorods produced stronger mass signals. Organic molecules in the tissue were not detected and did not inhibit the LDI processes of the gold nanorods in the tissue. Because of the selective LDI processes of the gold nanorods, the distribution of gold in the liver was successfully determined by imaging mass spectrometry.

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JF - Chemistry Letters

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ER -

Imaging mass spectrometry of intravenously injected gold nanorods in mice

Abstract

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