Immunocytological detection of T-lymphocyte subpopulation in schistosomiasis mansoni patients.

M. M. Abdel Rahman, O. A. Nassar, S. A. Eid, M. F. Mohamed, A. H. Sabry

Research output: Contribution to journalArticle

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Abstract

Pan T-lymphocytes, T4 (helper cells), T8 (suppressor cells) and T4/T8 ratio were studied in 51 bilharzial patients as well as 30 healthy controls using monoclonal antibodies and indirect immunofluorescence technique. There was no significant alteration in cell mediated immunity in early non complicated schistosomal infection with the advance of the disease and the development of granuloma cell mediated immunity was markedly decreased as evidenced by significant reduction in pan T-lymphocytes, T4 (helper) cells as well as T4/T8 ratio in hepatosplenic group in comparison to healthy controls. Splenomegaly in such cases may play an addtiinoa lrole in the immunosuppression.

Original languageEnglish
Pages (from-to)445-454
Number of pages10
JournalJournal of the Egyptian Society of Parasitology
Volume23
Issue number2
Publication statusPublished - Aug 1 1993
Externally publishedYes

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CD4-Positive T-Lymphocytes
Schistosomiasis mansoni
CD4-CD8 Ratio
Lymphocyte Subsets
Helper-Inducer T-Lymphocytes
Cellular Immunity
CD8-Positive T-Lymphocytes
Schistosoma
T-Lymphocytes
Splenomegaly
Indirect Fluorescent Antibody Technique
Granuloma
Immunosuppression
Monoclonal Antibodies
Infection

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Abdel Rahman, M. M., Nassar, O. A., Eid, S. A., Mohamed, M. F., & Sabry, A. H. (1993). Immunocytological detection of T-lymphocyte subpopulation in schistosomiasis mansoni patients. Journal of the Egyptian Society of Parasitology, 23(2), 445-454.

Immunocytological detection of T-lymphocyte subpopulation in schistosomiasis mansoni patients. / Abdel Rahman, M. M.; Nassar, O. A.; Eid, S. A.; Mohamed, M. F.; Sabry, A. H.

In: Journal of the Egyptian Society of Parasitology, Vol. 23, No. 2, 01.08.1993, p. 445-454.

Research output: Contribution to journalArticle

Abdel Rahman, MM, Nassar, OA, Eid, SA, Mohamed, MF & Sabry, AH 1993, 'Immunocytological detection of T-lymphocyte subpopulation in schistosomiasis mansoni patients.', Journal of the Egyptian Society of Parasitology, vol. 23, no. 2, pp. 445-454.
Abdel Rahman, M. M. ; Nassar, O. A. ; Eid, S. A. ; Mohamed, M. F. ; Sabry, A. H. / Immunocytological detection of T-lymphocyte subpopulation in schistosomiasis mansoni patients. In: Journal of the Egyptian Society of Parasitology. 1993 ; Vol. 23, No. 2. pp. 445-454.
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