TY - JOUR
T1 - Impact of a learning health system on acute care and medical complications after intracerebral hemorrhage
AU - Matsumoto, Koutarou
AU - Nohara, Yasunobu
AU - Wakata, Yoshifumi
AU - Yamashita, Takanori
AU - Kozuma, Yukio
AU - Sugeta, Rui
AU - Yamakawa, Miki
AU - Yamauchi, Fumiko
AU - Miyashita, Eri
AU - Takezaki, Tatsuya
AU - Yamashiro, Shigeo
AU - Nishi, Toru
AU - Machida, Jiro
AU - Soejima, Hidehisa
AU - Kamouchi, Masahiro
AU - Nakashima, Naoki
N1 - Funding Information:
This study was supported by the Japan Society for the Promotion of Science (JSPS), Grant‐in‐Aid for Scientific Research (KAKENHI: 17H04143); Health Labour Sciences Research Grant (19AC0101: 19196406); and Japan Agency for Medical Research and Development (AMED: 16hk0102038h0001, 19213182). We thank Eleanor Scharf, MSc(A), and Ryan Chastain‐Gross, PhD, from Edanz Group for editing a draft of this manuscript.
Publisher Copyright:
© 2020 The Authors. Learning Health Systems published by Wiley Periodicals, Inc. on behalf of the University of Michigan.
PY - 2021/4
Y1 - 2021/4
N2 - Introduction: Patients with stroke often experience pneumonia during the acute stage after stroke onset. Oral care may be effective in reducing the risk of stroke-associated pneumonia (SAP). We aimed to determine the changes in oral care, as well as the incidence of SAP, in patients with intracerebral hemorrhage, following implementation of a learning health system in our hospital. Methods: We retrospectively analyzed the data of 1716 patients with intracerebral hemorrhage who were hospitalized at a single stroke center in Japan between January 2012 and December 2018. Data were stratified on the basis of three periods of evolving oral care: period A, during which conventional, empirically driven oral care was provided (n = 725); period B, during which standardized oral care was introduced, with SAP prophylaxis based on known risk factors (n = 469); and period C, during which oral care was risk-appropriate based on learning health system data (n = 522). Logistic regression analysis was performed to evaluate associations between each of the three treatment approaches and the risk of SAP. Results: Among the included patients, the mean age was 71.3 ± 13.6 years; 52.6% of patients were men. During the course of each period, the frequency of oral care within 24 hours of admission increased (P <.001), as did the adherence rate to oral care ≥3 times per day (P <.001). After adjustment for confounding factors, a change in the risk of SAP was not observed in period B; however, the risk significantly decreased in period C (odds ratio 0.61; 95% confidence interval 0.43-0.87) compared with period A. These associations were maintained for SAP diagnosed using strict clinical criteria or after exclusion of 174 patients who underwent neurosurgical treatment. Conclusions: Risk-appropriate care informed by the use of learning health system data could improve care and potentially reduce the risk of SAP in patients with intracerebral hemorrhage in the acute stage.
AB - Introduction: Patients with stroke often experience pneumonia during the acute stage after stroke onset. Oral care may be effective in reducing the risk of stroke-associated pneumonia (SAP). We aimed to determine the changes in oral care, as well as the incidence of SAP, in patients with intracerebral hemorrhage, following implementation of a learning health system in our hospital. Methods: We retrospectively analyzed the data of 1716 patients with intracerebral hemorrhage who were hospitalized at a single stroke center in Japan between January 2012 and December 2018. Data were stratified on the basis of three periods of evolving oral care: period A, during which conventional, empirically driven oral care was provided (n = 725); period B, during which standardized oral care was introduced, with SAP prophylaxis based on known risk factors (n = 469); and period C, during which oral care was risk-appropriate based on learning health system data (n = 522). Logistic regression analysis was performed to evaluate associations between each of the three treatment approaches and the risk of SAP. Results: Among the included patients, the mean age was 71.3 ± 13.6 years; 52.6% of patients were men. During the course of each period, the frequency of oral care within 24 hours of admission increased (P <.001), as did the adherence rate to oral care ≥3 times per day (P <.001). After adjustment for confounding factors, a change in the risk of SAP was not observed in period B; however, the risk significantly decreased in period C (odds ratio 0.61; 95% confidence interval 0.43-0.87) compared with period A. These associations were maintained for SAP diagnosed using strict clinical criteria or after exclusion of 174 patients who underwent neurosurgical treatment. Conclusions: Risk-appropriate care informed by the use of learning health system data could improve care and potentially reduce the risk of SAP in patients with intracerebral hemorrhage in the acute stage.
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U2 - 10.1002/lrh2.10223
DO - 10.1002/lrh2.10223
M3 - Article
AN - SCOPUS:85081204523
SN - 2379-6146
VL - 5
JO - Learning Health Systems
JF - Learning Health Systems
IS - 2
M1 - e10223
ER -
