Impact of urinary arsenic level on simple diffuse goiter

Md Sharif Hossain, Fatema Begum

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The impacts of urinary arsenic level on simple diffuse goiter was studied in Bangladeshi population. A correlation of urinary iodine, radioiodine uptake, thyroid stimulating hormone (THS) and free thyroxin (FT4) levels was made on urinary arsenic level using a case-control analytical study. Out of 85 subjects 45 were considered for experimental group with simple diffuse goiter and rest 40 were considered for healthy control group without any thyroid disease. From the experimental results it has been found that iodine deficiency is not only the factor of causing simple diffuse goiter, but arsenic level is also one of the most important factors of causing simple diffuse goiter. It has also been found that the radioiodine uptake levels at 2 hours and 24 hours and the serum FT4 have negative impacts on arsenic levels for both the experimental and control group. Their impacts are not statistically significant except the variable radioiodine uptake levels at 24 hours. The serum TSH has positive impact on arsenic level for both experimental and control groups but not statistically significant. The estimated results revealed that the variable radioiodine uptake level at 24 hours play the significant role for reducing arsenic level.

Original languageEnglish
Pages (from-to)161-168
Number of pages8
JournalDhaka University Journal of Pharmaceutical Sciences
Issue number2
Publication statusPublished - 2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science
  • Pharmacology (medical)


Dive into the research topics of 'Impact of urinary arsenic level on simple diffuse goiter'. Together they form a unique fingerprint.

Cite this