Importance of Receptor Conformations in Docking Calculation-Based Risk Assessment for Endocrine Disruptors against Estrogen Receptor α

Chemistry

• Agonist 100%
• Antagonist 83%
• Conformation 55%
• Ligand 16%
• Endocrine Disruptor 11%
• Estrogen 11%
• Drug Discovery 11%
• Risk Assessment 11%
• Procedure 5%
• Number 5%
• Kd 5%
• Reaction Selectivity 5%
• Bioactivity 5%
• Bisphenol A 5%
• Estradiol 5%
• Diethylstilbestrol 5%
• Estrogen Receptor Antagonist 5%
• Estrogen Receptor Agonist 5%
• Raloxifene 5%
• Partial Agonist 5%

Medicine and Dentistry

• Receptor 38%
• Estrogen Receptor 16%
• DNA Template 11%
• Endocrine Disruptor 11%
• Carboxy Terminal Sequence 11%
• In Silico 11%
• Ligand Binding 11%
• Receptor Binding 11%
• Biological Product 5%
• Aptitude 5%
• Biological Activity 5%
• Estradiol 5%
• Binding Affinity 5%
• Ligand 5%
• Bisphenol A 5%
• Selectivity 5%
• Estrogen Receptor Antagonist 5%
• Diethylstilbestrol 5%
• Side Effect 5%
• Raloxifene 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Receptor 38%
• Risk Assessment 22%
• Estrogen Receptor 16%
• Endocrine Disruptor 11%
• Diethylstilbestrol 11%
• Ligand 5%
• Biological Product 5%
• 4,4' Isopropylidenediphenol 5%
• Receptor Agonist 5%
• Afimoxifene 5%
• Estrogen Receptor Antagonist 5%
• Partial Agonist 5%
• Raloxifene 5%
• Side Effect 5%