Improved isotopic deuterium labeling at the diastereotopic methyl group of leucine

A synthetic route to (4S)- and (4R)-[5-2H 1]leucine

Noriaki Yamauchi, Satoshi Endoh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Two isotopomers of deuterium-labeled leucine in the diastereotopic methyl group were synthesized from inexpensively available (R)- and (S)-citronellol in a more convenient way than by previous methods.

Original languageEnglish
Pages (from-to)276-278
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume70
Issue number1
DOIs
Publication statusPublished - Feb 2 2006

Fingerprint

Deuterium
Leucine
Labeling
citronellol
leucine methyl ester

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

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title = "Improved isotopic deuterium labeling at the diastereotopic methyl group of leucine: A synthetic route to (4S)- and (4R)-[5-2H 1]leucine",
abstract = "Two isotopomers of deuterium-labeled leucine in the diastereotopic methyl group were synthesized from inexpensively available (R)- and (S)-citronellol in a more convenient way than by previous methods.",
author = "Noriaki Yamauchi and Satoshi Endoh",
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