TY - JOUR
T1 - Improvement of artemisinin production by chitosan in hairy root cultures of Artemisia annua L.
AU - Putalun, Waraporn
AU - Luealon, Wanwimon
AU - De-Eknamkul, Wanchai
AU - Tanaka, Hiroyuki
AU - Shoyama, Yukihiro
N1 - Funding Information:
Acknowledgements This work was supported by a grant from the National Center for Genetic and Biotechnology (BIOTEC), Thailand and Asian Core Program (Medicinal Plant Breeding Division) under the Japan Society for the Promotion of Science (JSPS).
PY - 2007/7
Y1 - 2007/7
N2 - Artemisinin production by hairy roots of Artemisia annua L. was increased 6-fold to 1.8 μg mg-1 dry wt over 6 days by adding 150 mg chitosan l-1. The increase was dose-dependent. Similar treatment of hairy roots with methyl jasmonate (0.2 mM) or yeast extract (2 mg ml-1) increased artemisinin production to 1.5 and 0.9 μg mg-1 dry wt, respectively.
AB - Artemisinin production by hairy roots of Artemisia annua L. was increased 6-fold to 1.8 μg mg-1 dry wt over 6 days by adding 150 mg chitosan l-1. The increase was dose-dependent. Similar treatment of hairy roots with methyl jasmonate (0.2 mM) or yeast extract (2 mg ml-1) increased artemisinin production to 1.5 and 0.9 μg mg-1 dry wt, respectively.
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U2 - 10.1007/s10529-007-9368-8
DO - 10.1007/s10529-007-9368-8
M3 - Article
C2 - 17426924
AN - SCOPUS:34249048050
SN - 0141-5492
VL - 29
SP - 1143
EP - 1146
JO - Biotechnology Letters
JF - Biotechnology Letters
IS - 7
ER -