Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS.

Kazuhiro Tobiishi, Shigeru Suzuki, Takashi Todaka, Hironori Hirakawa, Tsuguhide Hori, Jumboku Kajiwara, Teruaki Hirata, Takao Iida, Hiroshi Uchi, Masutaka Furue

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2 Citations (Scopus)

Abstract

Hydroxylated polychlorinated biphenyls (OH-PCBs) are well known as metabolites of PCBs in the human body. We improved a measurement method for OH-PCBs in blood samples using LC/MS/MS. A new 2 microm particle column was used, and the analytical conditions for the LC/MS/MS measurements were optimized. The improved method is more sensitive than the conventional method for 5g blood samples. And, this method is effective at determining the concentrations of OH-PCBs, PCBs and dioxins from the same sample without special treatment of the sample such as derivatization.

Original languageEnglish
Pages (from-to)128-135
Number of pages8
JournalUnknown Journal
Volume104
Issue number4
Publication statusPublished - Apr 2013

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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  • Cite this

    Tobiishi, K., Suzuki, S., Todaka, T., Hirakawa, H., Hori, T., Kajiwara, J., Hirata, T., Iida, T., Uchi, H., & Furue, M. (2013). Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS. Unknown Journal, 104(4), 128-135.