Improvement of partial volume segmentation for brain tissue on diffusion tensor images using multiple-tensor estimation

Seiji Kumazawa, Takashi Yoshiura, Hiroshi Honda, Fukai Toyofuku

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

To improve evaluations of cortical and subcortical diffusivity in neurological diseases, it is necessary to improve the accuracy of brain diffusion tensor imaging (DTI) data segmentation. The conventional partial volume segmentation method fails to classify voxels with multiple white matter (WM) fiber orientations such as fiber-crossing regions. Our purpose was to improve the performance of segmentation by taking into account the partial volume effects due to both multiple tissue types and multiple WM fiber orientations. We quantitatively evaluated the overall performance of the proposed method using digital DTI phantom data. Moreover, we applied our method to human DTI data, and compared our results with those of a conventional method. In the phantom experiments, the conventional method and proposed method yielded almost the same root mean square error (RMSE) for gray matter (GM) and cerebrospinal fluid (CSF), while the RMSE in the proposed method was smaller than that in the conventional method for WM. The volume overlap measures between our segmentation results and the ground truth of the digital phantom were more than 0.8 in all three tissue types, and were greater than those in the conventional method. In visual comparisons for human data, the WM/GM/CSF regions obtained using our method were in better agreement with the corresponding regions depicted in the structural image than those obtained using the conventional method. The results of the digital phantom experiment and human data demonstrated that our method improved accuracy in the segmentation of brain tissue data on DTI compared to the conventional method.

Original languageEnglish
Pages (from-to)1131-1140
Number of pages10
JournalJournal of Digital Imaging
Volume26
Issue number6
DOIs
Publication statusPublished - Dec 1 2013

Fingerprint

Diffusion tensor imaging
Tensors
Brain
Tissue
Cerebrospinal fluid
Fiber reinforced materials
Mean square error
Diffusion Tensor Imaging
Experiments
Fibers
Cerebrospinal Fluid
Imaging Phantoms

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Science Applications

Cite this

Improvement of partial volume segmentation for brain tissue on diffusion tensor images using multiple-tensor estimation. / Kumazawa, Seiji; Yoshiura, Takashi; Honda, Hiroshi; Toyofuku, Fukai.

In: Journal of Digital Imaging, Vol. 26, No. 6, 01.12.2013, p. 1131-1140.

Research output: Contribution to journalArticle

Kumazawa, Seiji ; Yoshiura, Takashi ; Honda, Hiroshi ; Toyofuku, Fukai. / Improvement of partial volume segmentation for brain tissue on diffusion tensor images using multiple-tensor estimation. In: Journal of Digital Imaging. 2013 ; Vol. 26, No. 6. pp. 1131-1140.
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