Improvement of trapping efficiency of microbubbles by forming time division multiple acoustic focal points

Toi Sawaguchi, Ren Koda, Naoto Hosaka, Shinya Onogi, Takashi Mochizuki, Kohji Masuda

Research output: Contribution to journalArticle

Abstract

We have reported attempts to trap microcbubbles by ultrasound to increase density of microbubbles considering therapeutic efficiency. Because the form of blood vessel is complex, therapeutic efficiency will be improved by trapping in multiple areas simultaneously. However, there is a limitation of the number of transducers on body surface. In this study, we have developed a 2D-array transducer to form multiple focal points by designing the waveform. We observed microbubbles were trapped in 4 paths as shown in the figure. From the results, we confirmed the trapping efficiency was improved by comparing with the experiment of continuous emission with the same ultrasound energy above.

Original languageEnglish
Pages (from-to)O-327-O-328
JournalTransactions of Japanese Society for Medical and Biological Engineering
Volume52
DOIs
Publication statusPublished - Jan 1 2014
Externally publishedYes

Fingerprint

Acoustics
Transducers
Ultrasonics
Blood vessels
Experiments

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

Cite this

Improvement of trapping efficiency of microbubbles by forming time division multiple acoustic focal points. / Sawaguchi, Toi; Koda, Ren; Hosaka, Naoto; Onogi, Shinya; Mochizuki, Takashi; Masuda, Kohji.

In: Transactions of Japanese Society for Medical and Biological Engineering, Vol. 52, 01.01.2014, p. O-327-O-328.

Research output: Contribution to journalArticle

Sawaguchi, Toi ; Koda, Ren ; Hosaka, Naoto ; Onogi, Shinya ; Mochizuki, Takashi ; Masuda, Kohji. / Improvement of trapping efficiency of microbubbles by forming time division multiple acoustic focal points. In: Transactions of Japanese Society for Medical and Biological Engineering. 2014 ; Vol. 52. pp. O-327-O-328.
@article{97eb9f95f9fe4b06a36be822eb7c9c61,
title = "Improvement of trapping efficiency of microbubbles by forming time division multiple acoustic focal points",
abstract = "We have reported attempts to trap microcbubbles by ultrasound to increase density of microbubbles considering therapeutic efficiency. Because the form of blood vessel is complex, therapeutic efficiency will be improved by trapping in multiple areas simultaneously. However, there is a limitation of the number of transducers on body surface. In this study, we have developed a 2D-array transducer to form multiple focal points by designing the waveform. We observed microbubbles were trapped in 4 paths as shown in the figure. From the results, we confirmed the trapping efficiency was improved by comparing with the experiment of continuous emission with the same ultrasound energy above.",
author = "Toi Sawaguchi and Ren Koda and Naoto Hosaka and Shinya Onogi and Takashi Mochizuki and Kohji Masuda",
year = "2014",
month = "1",
day = "1",
doi = "10.11239/jsmbe.52.O-327",
language = "English",
volume = "52",
pages = "O--327--O--328",
journal = "BME = Bio medical engineering / henshu, Nihon ME Gakkai",
issn = "1347-443X",
publisher = "Japanese Society for Medical and Biological Engineering",

}

TY - JOUR

T1 - Improvement of trapping efficiency of microbubbles by forming time division multiple acoustic focal points

AU - Sawaguchi, Toi

AU - Koda, Ren

AU - Hosaka, Naoto

AU - Onogi, Shinya

AU - Mochizuki, Takashi

AU - Masuda, Kohji

PY - 2014/1/1

Y1 - 2014/1/1

N2 - We have reported attempts to trap microcbubbles by ultrasound to increase density of microbubbles considering therapeutic efficiency. Because the form of blood vessel is complex, therapeutic efficiency will be improved by trapping in multiple areas simultaneously. However, there is a limitation of the number of transducers on body surface. In this study, we have developed a 2D-array transducer to form multiple focal points by designing the waveform. We observed microbubbles were trapped in 4 paths as shown in the figure. From the results, we confirmed the trapping efficiency was improved by comparing with the experiment of continuous emission with the same ultrasound energy above.

AB - We have reported attempts to trap microcbubbles by ultrasound to increase density of microbubbles considering therapeutic efficiency. Because the form of blood vessel is complex, therapeutic efficiency will be improved by trapping in multiple areas simultaneously. However, there is a limitation of the number of transducers on body surface. In this study, we have developed a 2D-array transducer to form multiple focal points by designing the waveform. We observed microbubbles were trapped in 4 paths as shown in the figure. From the results, we confirmed the trapping efficiency was improved by comparing with the experiment of continuous emission with the same ultrasound energy above.

UR - http://www.scopus.com/inward/record.url?scp=84939421888&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84939421888&partnerID=8YFLogxK

U2 - 10.11239/jsmbe.52.O-327

DO - 10.11239/jsmbe.52.O-327

M3 - Article

VL - 52

SP - O-327-O-328

JO - BME = Bio medical engineering / henshu, Nihon ME Gakkai

JF - BME = Bio medical engineering / henshu, Nihon ME Gakkai

SN - 1347-443X

ER -