In utero sonographic findings of giant hepatic hemangioma and associated perinatal complications: A report of two cases

Hiromi Imai, Nobuhiro Hidaka, Takeshi Murakami, Saki Kido, Yasuo Yumoto, Kotaro Fukushima, Kiyoko Kato

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

It is uncommon to diagnose fetal hepatic hemangioma during the antenatal period. We describe herein two patients with a giant hepatic hemangioma detected antenatally, both with perinatal complications. In Case 1, a fetal intra-abdominal mass, measuring 63mm×50mm×74mm, was observed below the right lobe of the liver, and the presumptive antenatal diagnosis of hepatic hemangioma was made at 37weeks of gestation. Antenatal imaging suggested an intratumoral hemorrhage, but postnatal clinical findings refuted this diagnosis. However, progressive thrombocytopenia and coagulopathy were noted just after birth, resulting in the diagnosis of Kasabach-Merritt syndrome. In Case 2, our ultrasound examination performed at 40weeks of gestation revealed a mixed solid and cystic hepatic tumor, measuring 99mm×54mm. Further, antenatal sonography revealed cardiomegaly, increased descending-aorta velocity, atrioventricular valvular regurgitation, and a dilated inferior vena cava, suggesting high-output cardiac insufficiency. Giant hepatic hemangiomas can lead to severe complications such as cardiac insufficiency and Kasabach-Merritt syndrome, and these complications may occur during the fetal or early neonatal period. Detailed prenatal evaluation using fetal imaging and cord-blood sampling is important to determine proper antenatal management of patients with giant hepatic hemangiomas and to allow for prompt postnatal treatment.

Original languageEnglish
Pages (from-to)46-51
Number of pages6
JournalJournal of Medical Ultrasound
Volume23
Issue number1
DOIs
Publication statusPublished - Mar 1 2015

Fingerprint

Hemangioma
Liver
Kasabach-Merritt Syndrome
Cordocentesis
High Cardiac Output
Pregnancy
Cardiomegaly
Inferior Vena Cava
Prenatal Diagnosis
Thoracic Aorta
Thrombocytopenia
Ultrasonography
Parturition
Hemorrhage
Neoplasms

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

In utero sonographic findings of giant hepatic hemangioma and associated perinatal complications : A report of two cases. / Imai, Hiromi; Hidaka, Nobuhiro; Murakami, Takeshi; Kido, Saki; Yumoto, Yasuo; Fukushima, Kotaro; Kato, Kiyoko.

In: Journal of Medical Ultrasound, Vol. 23, No. 1, 01.03.2015, p. 46-51.

Research output: Contribution to journalArticle

@article{36f8ab5a0b804f4ca7a8b11d4d858076,
title = "In utero sonographic findings of giant hepatic hemangioma and associated perinatal complications: A report of two cases",
abstract = "It is uncommon to diagnose fetal hepatic hemangioma during the antenatal period. We describe herein two patients with a giant hepatic hemangioma detected antenatally, both with perinatal complications. In Case 1, a fetal intra-abdominal mass, measuring 63mm×50mm×74mm, was observed below the right lobe of the liver, and the presumptive antenatal diagnosis of hepatic hemangioma was made at 37weeks of gestation. Antenatal imaging suggested an intratumoral hemorrhage, but postnatal clinical findings refuted this diagnosis. However, progressive thrombocytopenia and coagulopathy were noted just after birth, resulting in the diagnosis of Kasabach-Merritt syndrome. In Case 2, our ultrasound examination performed at 40weeks of gestation revealed a mixed solid and cystic hepatic tumor, measuring 99mm×54mm. Further, antenatal sonography revealed cardiomegaly, increased descending-aorta velocity, atrioventricular valvular regurgitation, and a dilated inferior vena cava, suggesting high-output cardiac insufficiency. Giant hepatic hemangiomas can lead to severe complications such as cardiac insufficiency and Kasabach-Merritt syndrome, and these complications may occur during the fetal or early neonatal period. Detailed prenatal evaluation using fetal imaging and cord-blood sampling is important to determine proper antenatal management of patients with giant hepatic hemangiomas and to allow for prompt postnatal treatment.",
author = "Hiromi Imai and Nobuhiro Hidaka and Takeshi Murakami and Saki Kido and Yasuo Yumoto and Kotaro Fukushima and Kiyoko Kato",
year = "2015",
month = "3",
day = "1",
doi = "10.1016/j.jmu.2014.10.005",
language = "English",
volume = "23",
pages = "46--51",
journal = "Journal of Medical Ultrasound",
issn = "0929-6441",
publisher = "Elsevier (Singapore) Pte Ltd",
number = "1",

}

TY - JOUR

T1 - In utero sonographic findings of giant hepatic hemangioma and associated perinatal complications

T2 - A report of two cases

AU - Imai, Hiromi

AU - Hidaka, Nobuhiro

AU - Murakami, Takeshi

AU - Kido, Saki

AU - Yumoto, Yasuo

AU - Fukushima, Kotaro

AU - Kato, Kiyoko

PY - 2015/3/1

Y1 - 2015/3/1

N2 - It is uncommon to diagnose fetal hepatic hemangioma during the antenatal period. We describe herein two patients with a giant hepatic hemangioma detected antenatally, both with perinatal complications. In Case 1, a fetal intra-abdominal mass, measuring 63mm×50mm×74mm, was observed below the right lobe of the liver, and the presumptive antenatal diagnosis of hepatic hemangioma was made at 37weeks of gestation. Antenatal imaging suggested an intratumoral hemorrhage, but postnatal clinical findings refuted this diagnosis. However, progressive thrombocytopenia and coagulopathy were noted just after birth, resulting in the diagnosis of Kasabach-Merritt syndrome. In Case 2, our ultrasound examination performed at 40weeks of gestation revealed a mixed solid and cystic hepatic tumor, measuring 99mm×54mm. Further, antenatal sonography revealed cardiomegaly, increased descending-aorta velocity, atrioventricular valvular regurgitation, and a dilated inferior vena cava, suggesting high-output cardiac insufficiency. Giant hepatic hemangiomas can lead to severe complications such as cardiac insufficiency and Kasabach-Merritt syndrome, and these complications may occur during the fetal or early neonatal period. Detailed prenatal evaluation using fetal imaging and cord-blood sampling is important to determine proper antenatal management of patients with giant hepatic hemangiomas and to allow for prompt postnatal treatment.

AB - It is uncommon to diagnose fetal hepatic hemangioma during the antenatal period. We describe herein two patients with a giant hepatic hemangioma detected antenatally, both with perinatal complications. In Case 1, a fetal intra-abdominal mass, measuring 63mm×50mm×74mm, was observed below the right lobe of the liver, and the presumptive antenatal diagnosis of hepatic hemangioma was made at 37weeks of gestation. Antenatal imaging suggested an intratumoral hemorrhage, but postnatal clinical findings refuted this diagnosis. However, progressive thrombocytopenia and coagulopathy were noted just after birth, resulting in the diagnosis of Kasabach-Merritt syndrome. In Case 2, our ultrasound examination performed at 40weeks of gestation revealed a mixed solid and cystic hepatic tumor, measuring 99mm×54mm. Further, antenatal sonography revealed cardiomegaly, increased descending-aorta velocity, atrioventricular valvular regurgitation, and a dilated inferior vena cava, suggesting high-output cardiac insufficiency. Giant hepatic hemangiomas can lead to severe complications such as cardiac insufficiency and Kasabach-Merritt syndrome, and these complications may occur during the fetal or early neonatal period. Detailed prenatal evaluation using fetal imaging and cord-blood sampling is important to determine proper antenatal management of patients with giant hepatic hemangiomas and to allow for prompt postnatal treatment.

UR - http://www.scopus.com/inward/record.url?scp=84929268565&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929268565&partnerID=8YFLogxK

U2 - 10.1016/j.jmu.2014.10.005

DO - 10.1016/j.jmu.2014.10.005

M3 - Article

AN - SCOPUS:84929268565

VL - 23

SP - 46

EP - 51

JO - Journal of Medical Ultrasound

JF - Journal of Medical Ultrasound

SN - 0929-6441

IS - 1

ER -