In vitro apatite deposition and biodegradation of porous gelatin-silicate hybrids derived from sol-gel process

L. Ren, K. Tsuru, S. Hayakawa, A. Osaka

Research output: Contribution to journalConference article

1 Citation (Scopus)

Abstract

Ca(II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca(II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.

Original languageEnglish
Pages (from-to)CC10.6.1-CC10.6.6
JournalMaterials Research Society Symposium - Proceedings
Volume628
DOIs
Publication statusPublished - Jan 1 2000
EventOrganic/Inorganic Hybrid Materials-2000 - San Francisco, CA, United States
Duration: Apr 24 2000Apr 28 2000

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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