In vitro apatite formation on organic polymers modified with a silane coupling reagent

Yuki Shirosaki, Masaaki Kubo, Seisuke Takashima, Kanji Tsuru, Satoshi Hayakawa, Akiyoshi Osaka

Research output: Contribution to journalArticle

11 Citations (Scopus)


γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted to high-density polyethylene, polyamide and silicone rubber substrates by the emulsion polymerization procedure in order to provide these organic polymers with in vitro apatite-forming ability. The contact angles towards distilled water of the γ-MPS-grafted specimens were lower than those of the original organic polymer specimens, indicating that the grafted substrates were more hydrophilic. The in vitro apatite formation in a simulated body fluid (Kokubo solution) was confirmed for several of the γ-MPS-grafted specimens.

Original languageEnglish
Pages (from-to)335-340
Number of pages6
JournalJournal of the Royal Society Interface
Issue number4
Publication statusPublished - Jan 1 2005


All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biochemistry
  • Biomedical Engineering

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