TY - JOUR
T1 - In vitro chemosensitivity test
T2 - succinate dehydrogenase inhibition (SDI) test
AU - Maehara, Y.
AU - Kohnoe, S.
AU - Emi, Y.
AU - Sakaguchi, Y.
AU - Sugimachi, K.
PY - 1990/1/1
Y1 - 1990/1/1
N2 - The succinate dehydrogenase inhibition (SDI) test was used for determining chemosensitivity of various human tumors. This test was based on the correlation between the cellular succinate dehydrogenase activity as determined by 3-(4,5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2H tetrazolium bromide (MTT), and cell viability. The chemosensitivity varied in the tissue. Some factors are involved in the chemosensitivity, that is origin of a tumor, tissue differentiation and tissue DNA synthetic activity. This test is a convenient method for clinical use and provides important information about chemosensitivity.
AB - The succinate dehydrogenase inhibition (SDI) test was used for determining chemosensitivity of various human tumors. This test was based on the correlation between the cellular succinate dehydrogenase activity as determined by 3-(4,5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2H tetrazolium bromide (MTT), and cell viability. The chemosensitivity varied in the tissue. Some factors are involved in the chemosensitivity, that is origin of a tumor, tissue differentiation and tissue DNA synthetic activity. This test is a convenient method for clinical use and provides important information about chemosensitivity.
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M3 - Article
C2 - 2308218
AN - SCOPUS:0025030929
VL - 38
SP - 14
EP - 18
JO - Rinsho byori. The Japanese journal of clinical pathology
JF - Rinsho byori. The Japanese journal of clinical pathology
SN - 0047-1860
IS - 1
ER -