In vitro evaluation of the cytocompatibility of a glass-ionomer cement sealer

Y. Yoshimine, M. Yamamoto, T. Ogasawara, Y. Koishi, K. Tanabe, I. Hashiguchi, A. Akamine

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The purpose of this study was to evaluate the cytocompatibility of two different types of root canal sealers in cell culture. Human periodontal ligament cells were cultured with set materials from an experimental glass-ionomer cement sealer (KT-308) and a commercially available zinc oxide-eugenol-based sealer (Canals) for 1, 3, and 7 days. Cytotoxic effects were evaluated from the morphological changes under a light microscope. Canals induced severe degenerative alteration of human periodontal ligament cells. In contrast, human periodontal ligament cells adjacent to KT-308 showed normal morphology and growth during the culture period. These results suggest that the glass-ionomer cement sealer, KT-308, is cytocompatible and has good potential as a root canal sealer.

Original languageEnglish
Pages (from-to)453-455
Number of pages3
JournalJournal of Endodontics
Volume29
Issue number7
DOIs
Publication statusPublished - Jul 2003

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

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