In vitro osteoconductivity evaluation of alumina treated hydrothermally in CaCl2 solution

Abdullah Al-Mahmood Tarique, Kanji Tsuru, Michito Maruta, Akari Takeuchi, Shigeki Matsuya, Yoshihiro Terada, Kunio Ishikawa

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Alumina (Al2O3) is classified as bioinert materials and thus, no direct bonding to bone was observed when implanted. In the present investigation, possibility of osteoconductive Al2O3 was evaluated based on hydrothermal treatment in calcium chloride (CaCl2) solution. Based on X-ray photoelectron spectroscopy measurement, Ca 2p peaks were detected on Al2O3 after hydrothermal treatment with 10 and 50mmol/L CaCl2 solution at 125°C. The Ca2p peak intensity for Al2O3 treated with 50mmol/L CaCl2 was higher than that treated with 10mmol/L CaCl2. Then, in vitro osteoconductivity screening evaluation was made using simulated body fluid (SBF). After being soaked in SBF for 14 days, calcium phosphate deposition could be observed on Al2O 3 treated with 10 and 50mmol/L CaCl2 solution at 125°C for 7 days whereas no deposition was observed on Al2O3 treated at 150 and 200°C as well as non-treated Al2O3. We concluded, therefore, osteoconductive Al2O3 could be fabricated based on the hydrothermal treatment of bioinert Al2O 3 with CaCl2.

Original languageEnglish
Pages (from-to)512-515
Number of pages4
JournalJournal of the Ceramic Society of Japan
Volume118
Issue number1378
DOIs
Publication statusPublished - Jun 2010

Fingerprint

Aluminum Oxide
Alumina
body fluids
aluminum oxides
Body fluids
evaluation
calcium chlorides
Calcium Chloride
Calcium chloride
calcium phosphates
Calcium phosphate
bones
Screening
Bone
screening
X ray photoelectron spectroscopy
photoelectron spectroscopy
x rays

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Chemistry(all)
  • Condensed Matter Physics
  • Materials Chemistry

Cite this

In vitro osteoconductivity evaluation of alumina treated hydrothermally in CaCl2 solution. / Al-Mahmood Tarique, Abdullah; Tsuru, Kanji; Maruta, Michito; Takeuchi, Akari; Matsuya, Shigeki; Terada, Yoshihiro; Ishikawa, Kunio.

In: Journal of the Ceramic Society of Japan, Vol. 118, No. 1378, 06.2010, p. 512-515.

Research output: Contribution to journalArticle

Al-Mahmood Tarique, A, Tsuru, K, Maruta, M, Takeuchi, A, Matsuya, S, Terada, Y & Ishikawa, K 2010, 'In vitro osteoconductivity evaluation of alumina treated hydrothermally in CaCl2 solution', Journal of the Ceramic Society of Japan, vol. 118, no. 1378, pp. 512-515. https://doi.org/10.2109/jcersj2.118.512
Al-Mahmood Tarique A, Tsuru K, Maruta M, Takeuchi A, Matsuya S, Terada Y et al. In vitro osteoconductivity evaluation of alumina treated hydrothermally in CaCl2 solution. Journal of the Ceramic Society of Japan. 2010 Jun;118(1378):512-515. https://doi.org/10.2109/jcersj2.118.512
Al-Mahmood Tarique, Abdullah ; Tsuru, Kanji ; Maruta, Michito ; Takeuchi, Akari ; Matsuya, Shigeki ; Terada, Yoshihiro ; Ishikawa, Kunio. / In vitro osteoconductivity evaluation of alumina treated hydrothermally in CaCl2 solution. In: Journal of the Ceramic Society of Japan. 2010 ; Vol. 118, No. 1378. pp. 512-515.
@article{a2253bb8fbb94eb588c8e3a586654cb3,
title = "In vitro osteoconductivity evaluation of alumina treated hydrothermally in CaCl2 solution",
abstract = "Alumina (Al2O3) is classified as bioinert materials and thus, no direct bonding to bone was observed when implanted. In the present investigation, possibility of osteoconductive Al2O3 was evaluated based on hydrothermal treatment in calcium chloride (CaCl2) solution. Based on X-ray photoelectron spectroscopy measurement, Ca 2p peaks were detected on Al2O3 after hydrothermal treatment with 10 and 50mmol/L CaCl2 solution at 125°C. The Ca2p peak intensity for Al2O3 treated with 50mmol/L CaCl2 was higher than that treated with 10mmol/L CaCl2. Then, in vitro osteoconductivity screening evaluation was made using simulated body fluid (SBF). After being soaked in SBF for 14 days, calcium phosphate deposition could be observed on Al2O 3 treated with 10 and 50mmol/L CaCl2 solution at 125°C for 7 days whereas no deposition was observed on Al2O3 treated at 150 and 200°C as well as non-treated Al2O3. We concluded, therefore, osteoconductive Al2O3 could be fabricated based on the hydrothermal treatment of bioinert Al2O 3 with CaCl2.",
author = "{Al-Mahmood Tarique}, Abdullah and Kanji Tsuru and Michito Maruta and Akari Takeuchi and Shigeki Matsuya and Yoshihiro Terada and Kunio Ishikawa",
year = "2010",
month = "6",
doi = "10.2109/jcersj2.118.512",
language = "English",
volume = "118",
pages = "512--515",
journal = "Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan",
issn = "1882-0743",
publisher = "Ceramic Society of Japan/Nippon Seramikkusu Kyokai",
number = "1378",

}

TY - JOUR

T1 - In vitro osteoconductivity evaluation of alumina treated hydrothermally in CaCl2 solution

AU - Al-Mahmood Tarique, Abdullah

AU - Tsuru, Kanji

AU - Maruta, Michito

AU - Takeuchi, Akari

AU - Matsuya, Shigeki

AU - Terada, Yoshihiro

AU - Ishikawa, Kunio

PY - 2010/6

Y1 - 2010/6

N2 - Alumina (Al2O3) is classified as bioinert materials and thus, no direct bonding to bone was observed when implanted. In the present investigation, possibility of osteoconductive Al2O3 was evaluated based on hydrothermal treatment in calcium chloride (CaCl2) solution. Based on X-ray photoelectron spectroscopy measurement, Ca 2p peaks were detected on Al2O3 after hydrothermal treatment with 10 and 50mmol/L CaCl2 solution at 125°C. The Ca2p peak intensity for Al2O3 treated with 50mmol/L CaCl2 was higher than that treated with 10mmol/L CaCl2. Then, in vitro osteoconductivity screening evaluation was made using simulated body fluid (SBF). After being soaked in SBF for 14 days, calcium phosphate deposition could be observed on Al2O 3 treated with 10 and 50mmol/L CaCl2 solution at 125°C for 7 days whereas no deposition was observed on Al2O3 treated at 150 and 200°C as well as non-treated Al2O3. We concluded, therefore, osteoconductive Al2O3 could be fabricated based on the hydrothermal treatment of bioinert Al2O 3 with CaCl2.

AB - Alumina (Al2O3) is classified as bioinert materials and thus, no direct bonding to bone was observed when implanted. In the present investigation, possibility of osteoconductive Al2O3 was evaluated based on hydrothermal treatment in calcium chloride (CaCl2) solution. Based on X-ray photoelectron spectroscopy measurement, Ca 2p peaks were detected on Al2O3 after hydrothermal treatment with 10 and 50mmol/L CaCl2 solution at 125°C. The Ca2p peak intensity for Al2O3 treated with 50mmol/L CaCl2 was higher than that treated with 10mmol/L CaCl2. Then, in vitro osteoconductivity screening evaluation was made using simulated body fluid (SBF). After being soaked in SBF for 14 days, calcium phosphate deposition could be observed on Al2O 3 treated with 10 and 50mmol/L CaCl2 solution at 125°C for 7 days whereas no deposition was observed on Al2O3 treated at 150 and 200°C as well as non-treated Al2O3. We concluded, therefore, osteoconductive Al2O3 could be fabricated based on the hydrothermal treatment of bioinert Al2O 3 with CaCl2.

UR - http://www.scopus.com/inward/record.url?scp=77953559101&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953559101&partnerID=8YFLogxK

U2 - 10.2109/jcersj2.118.512

DO - 10.2109/jcersj2.118.512

M3 - Article

AN - SCOPUS:77953559101

VL - 118

SP - 512

EP - 515

JO - Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan

JF - Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan

SN - 1882-0743

IS - 1378

ER -