In vitro screening of angiotensin I-converting enzyme inhibitory activities in traditional plant medicines of Indonesia and Peru

Yuji Tsutsumi, Nozomi Fujii, Tomoaki Nishida, Ryo Soda, Ko Ichi Oshiman

Research output: Contribution to journalArticle

Abstract

A total of 110 extracts from 83 Indonesian traditional plant medicines and from 11 samples from Peru were subjected to the screening of angiotensin 1-converting enzyme (ACE) inhibitors by the in vitro ACE inhibitory assay at a fixed concentration, and the IC50 values for the selected 17 extracts were determined. The 100% ethanol extract from Majakani (Quercus lusitanica) showed the highest inhibitory activity and its IC50 was 5.7 μg/ml.

Original languageEnglish
Pages (from-to)7-13
Number of pages7
JournalNatural Medicines
Volume54
Issue number1
Publication statusPublished - Feb 1 2000

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Peru
Indonesia
Angiotensins
Enzyme activity
Traditional Medicine
Peptidyl-Dipeptidase A
Inhibitory Concentration 50
Medicine
Screening
Quercus
Enzyme Assays
Enzyme Inhibitors
Angiotensin-Converting Enzyme Inhibitors
Assays
Ethanol
Enzymes
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Molecular Medicine

Cite this

In vitro screening of angiotensin I-converting enzyme inhibitory activities in traditional plant medicines of Indonesia and Peru. / Tsutsumi, Yuji; Fujii, Nozomi; Nishida, Tomoaki; Soda, Ryo; Oshiman, Ko Ichi.

In: Natural Medicines, Vol. 54, No. 1, 01.02.2000, p. 7-13.

Research output: Contribution to journalArticle

Tsutsumi, Yuji ; Fujii, Nozomi ; Nishida, Tomoaki ; Soda, Ryo ; Oshiman, Ko Ichi. / In vitro screening of angiotensin I-converting enzyme inhibitory activities in traditional plant medicines of Indonesia and Peru. In: Natural Medicines. 2000 ; Vol. 54, No. 1. pp. 7-13.
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