Increased and more heterogeneous gadoxetic acid uptake of the liver parenchyma after hepatitis c virus eradication by direct antiviral agent

Nobuhiro Fujita, Akihiro Nishie, Yoshiki Asayama, Kousei Ishigami, Tomohiro Nakayama, Yasuhiro Ushijima, Daisuke Kakihara, Yukihisa Takayama, Koichiro Morita, Keisuke Ishimatsu, Seiichiro Takao, Tomoharu Yoshizumi, Norihiro Furusyo, Hiroshi Honda

Research output: Contribution to journalArticlepeer-review

Abstract

We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. After sustained virological response, gadoxetic acid uptake of the liver parenchyma increased, but became heterogeneous. Our study proved that HCV eradication by DAA therapy could significantly affect gadoxetic acid uptake.

Original languageEnglish
Pages (from-to)389-393
Number of pages5
JournalMagnetic Resonance in Medical Sciences
Volume19
Issue number4
DOIs
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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