Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid Arthritis

Andrew J. McMichael, Takehiko Sasazuki, Hugh O. McDevitt, Rose O. Payne

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

Thirty‐nine patients with rheumatoid arthritis were HLA typed for the full range of A and B locus specificities and for Cw3 and Dw4. HLA‐Dw4 was significantly more frequent in patients (36%) than in controls (13%). The frequency of Cw3 was also increased, probably because this allele is in linkage disequilibrium with Dw4.

Original languageEnglish
Pages (from-to)1037-1042
Number of pages6
JournalArthritis & Rheumatism
Volume20
Issue number5
DOIs
Publication statusPublished - Jun 1977
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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    McMichael, A. J., Sasazuki, T., McDevitt, H. O., & Payne, R. O. (1977). Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid Arthritis. Arthritis & Rheumatism, 20(5), 1037-1042. https://doi.org/10.1002/art.1780200501