Abstract
We examined the effect of orally administering L-Ser-L-Tyr (SY) dipeptide on the brain of a serine deficiency disease model mouse to attain the efficient delivery of L-Tyr and L-Ser into the mouse brain. Oral SY administration increased the L-Tyr level more efficiently than L-Tyr administration with the same intake dose, but did not significantly affect the L-Ser level when compared with L-Ser administration.
| Original language | English |
|---|---|
| Pages (from-to) | 847-849 |
| Number of pages | 3 |
| Journal | Bioscience, Biotechnology and Biochemistry |
| Volume | 77 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jun 14 2013 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry
Cite this
Increased tyrosine in the brain and serum of mice by orally administering dipeptide SY. / Esaki, Kayoko; Ohmori, Taketo; Maebuchi, Motohiro; Nakamori, Toshihiro; Ohshima, Toshihisa; Furuya, Shigeki.
In: Bioscience, Biotechnology and Biochemistry, Vol. 77, No. 4, 14.06.2013, p. 847-849.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Increased tyrosine in the brain and serum of mice by orally administering dipeptide SY
AU - Esaki, Kayoko
AU - Ohmori, Taketo
AU - Maebuchi, Motohiro
AU - Nakamori, Toshihiro
AU - Ohshima, Toshihisa
AU - Furuya, Shigeki
PY - 2013/6/14
Y1 - 2013/6/14
N2 - We examined the effect of orally administering L-Ser-L-Tyr (SY) dipeptide on the brain of a serine deficiency disease model mouse to attain the efficient delivery of L-Tyr and L-Ser into the mouse brain. Oral SY administration increased the L-Tyr level more efficiently than L-Tyr administration with the same intake dose, but did not significantly affect the L-Ser level when compared with L-Ser administration.
AB - We examined the effect of orally administering L-Ser-L-Tyr (SY) dipeptide on the brain of a serine deficiency disease model mouse to attain the efficient delivery of L-Tyr and L-Ser into the mouse brain. Oral SY administration increased the L-Tyr level more efficiently than L-Tyr administration with the same intake dose, but did not significantly affect the L-Ser level when compared with L-Ser administration.
UR - http://www.scopus.com/inward/record.url?scp=84878804747&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878804747&partnerID=8YFLogxK
U2 - 10.1271/bbb.120747
DO - 10.1271/bbb.120747
M3 - Article
C2 - 23563534
AN - SCOPUS:84878804747
VL - 77
SP - 847
EP - 849
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
SN - 0916-8451
IS - 4
ER -