Increased tyrosine in the brain and serum of mice by orally administering dipeptide SY

Kayoko Esaki, Taketo Ohmori, Motohiro Maebuchi, Toshihiro Nakamori, Toshihisa Ohshima, Shigeki Furuya

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We examined the effect of orally administering L-Ser-L-Tyr (SY) dipeptide on the brain of a serine deficiency disease model mouse to attain the efficient delivery of L-Tyr and L-Ser into the mouse brain. Oral SY administration increased the L-Tyr level more efficiently than L-Tyr administration with the same intake dose, but did not significantly affect the L-Ser level when compared with L-Ser administration.

Original languageEnglish
Pages (from-to)847-849
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume77
Issue number4
DOIs
Publication statusPublished - 2013

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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