By sonication in MeOHN-m-(phenylboronic acid)-2,2'-bipyridine-5- carboxylamide easily formed its bidentate boronate sugar ligands. Solutions of the corresponding Cu(I) and Fe(II) complexes showed opposite CD effects for the D and the L form of the sugar. The stoichiometry of the metal complexes was determined by Job plots and by mass spectrometry. A macrocyclic structure, that includes ten cycles, is proposed as the most probable CD- active species.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry