Infant circulation model based on the electrophysiological cell model.

Yutaka Nobuaki, Akira Amano, Takao Shimayoshi, Jianyin Lu, Eun B. Shim, Tetsuya Matsuda

Research output: Contribution to journalArticle

Abstract

It is important to use a myocardial cell model to evaluate the effects of the drugs to the hemodynamic parameters. We developed an infant circulation model which incorporates an accurate myocardial cell model including a beta adrenergic system. The beta adrenergic system is essential mechanism for reproducing the response of baroreflex control system. The parameters of the published adult human circulation model were modified to fit the infant hemodynamic values. The guinea pig myocardial cell model was introduced to the circulation model whose baseline heart rate is close to that of an infant. The presented model is in good agreement with results obtained in physiological experiments.

Original languageEnglish
Pages (from-to)1010-1013
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Publication statusPublished - 2007
Externally publishedYes

Fingerprint

Adrenergic Agents
Hemodynamics
Baroreflex
Guinea Pigs
Heart Rate
Pharmaceutical Preparations
Control systems
Experiments

All Science Journal Classification (ASJC) codes

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Infant circulation model based on the electrophysiological cell model. / Nobuaki, Yutaka; Amano, Akira; Shimayoshi, Takao; Lu, Jianyin; Shim, Eun B.; Matsuda, Tetsuya.

In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 2007, p. 1010-1013.

Research output: Contribution to journalArticle

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