Influence of coil current configuration in magnetic stimulation of a nerve fiber in inhomogeneous and anisotropic conducting media

Akira Hyodo, Keiji Iramina, Shoogo Ueno

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this study, we used a computer simulation to investigate the effects of the coil current waveform and direction on the excitation processes of the nerve axon in inhomogeneous and anisotropic conducting media in magnetic stimulation. We assumed that the nerve axon was located in the media with 2 regions having different conductivities or electrical anisotropy that simulate different tissue types. The distribution of induced electric fields was calculated with the finite element method (FEM). The nerve fiber was modeled after equivalent electrical circuits having active nodes of Ranvier. The direction of the coil current at the intersection of a figure-eight coil was assumed to flow perpendicular to the nerve axon. We observed the excitation threshold when the coil current waveform and direction are changed with varying the electrical properties such as tissue electrical conductivity and anisotropy. The simulation results show that the threshold decreases with the increase of conductivity ratio between 2 regions and it also depends on the coil current waveform and direction. Biphasic coil current has lower threshold than monophasic one when the current direction is the same in both waveforms. The results also suggest that the tissue anisotropy strongly affects the excitation threshold. The threshold increases with the increase of tissue anisotropic ratio of longitudinal direction to the transverse one respect to the nerve axon. The results in this study give useful information to explain the experimental results of the magnetic stimulation of human peripheral nervous systems and the theoretical model is applicable to understand the characteristics in magnetic stimulation of both peripheral and central nervous systems.

Original languageEnglish
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages6501-6504
Number of pages4
ISBN (Print)9781424432967
DOIs
Publication statusPublished - Jan 1 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

Fingerprint

Nerve Fibers
Tissue
Anisotropy
Axons
Fibers
Neurology
Electric Conductivity
Peripheral Nervous System
Ranvier's Nodes
Electric properties
Electric fields
Finite element method
Computer Simulation
Direction compound
Networks (circuits)
Computer simulation
Theoretical Models
Central Nervous System

All Science Journal Classification (ASJC) codes

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

Cite this

Hyodo, A., Iramina, K., & Ueno, S. (2009). Influence of coil current configuration in magnetic stimulation of a nerve fiber in inhomogeneous and anisotropic conducting media. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 6501-6504). [5333594] IEEE Computer Society. https://doi.org/10.1109/IEMBS.2009.5333594

Influence of coil current configuration in magnetic stimulation of a nerve fiber in inhomogeneous and anisotropic conducting media. / Hyodo, Akira; Iramina, Keiji; Ueno, Shoogo.

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, 2009. p. 6501-6504 5333594.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hyodo, A, Iramina, K & Ueno, S 2009, Influence of coil current configuration in magnetic stimulation of a nerve fiber in inhomogeneous and anisotropic conducting media. in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009., 5333594, IEEE Computer Society, pp. 6501-6504, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, Minneapolis, MN, United States, 9/2/09. https://doi.org/10.1109/IEMBS.2009.5333594
Hyodo A, Iramina K, Ueno S. Influence of coil current configuration in magnetic stimulation of a nerve fiber in inhomogeneous and anisotropic conducting media. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society. 2009. p. 6501-6504. 5333594 https://doi.org/10.1109/IEMBS.2009.5333594
Hyodo, Akira ; Iramina, Keiji ; Ueno, Shoogo. / Influence of coil current configuration in magnetic stimulation of a nerve fiber in inhomogeneous and anisotropic conducting media. Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, 2009. pp. 6501-6504
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