Influence of dietary sorbose on lipogenesis in gold thioglucose-injected obese mice

Kita Kazumi, Furuse Mitsuhiro, Ik Yang Sung Ik Yang, Okumura Jun-Ichi

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

1. 1. The influence of dietary sorbose on food intake and fatty acid synthesis of the liver and epididymal white adipose tissue (EWAT) was investigated in gold thioglucose (GTG)-injected obese mice from 12 to 14 weeks of age. 2. 2. Sorbose was supplemented to a semi-purified diet at a level of 200 g/kg diet at the expense of sucrose. 3. 3. On the last day of the experiment, fatty acids synthesis in the liver and EWAT was measured using an i.p. injection [1-14C]sodium acetate. 4. 4. The decreases in body weight and food intake by dietary sorbose in GTG-injected obese mice were greater than those in control mice. 5. 5. Lipid content and fatty acid synthesis in the liver and EWAT of control mice were not influenced by dietary sorbose. 6. 6. In GTG-injected obese mice, the reduction of food intake by dietary sorbose suppressed fatty acid synthesis and lipid deposition in both liver and EWAT.

Original languageEnglish
Pages (from-to)249-253
Number of pages5
JournalInternational Journal of Biochemistry
Volume24
Issue number2
DOIs
Publication statusPublished - Feb 1992
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry

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