Influence of medical history in parents or siblings on the development of systemic lupus erythematosus among Japanese females

Kyushu Sapporo SLE (KYSS) Study Group

Research output: Contribution to journalArticle

Abstract

Objective: To examine the influence of medical history in parents or siblings on the development of systemic lupus erythematosus (SLE) among Japanese females. Methods: 160 female SLE patients and 660 female volunteers were studied in a case-control study. Unconditional logistic regression was used to compute OR and 95% CI, with adjustment for smoking, drinking, age and region. Results: The present study demonstrated that the risk of SLE was positively associated with family histories (i.e., medical histories in parents or siblings) of SLE (OR = 5.38, 95%CI = 1.43-20.20), rheumatoid arthritis (OR = 2.54, 95%CI = 1.08-5.96), collagen diseases (OR = 3.48, 95%CI = 1.87-6.48) and autoimmune diseases (OR = 5.25, 95%CI = 1.64-16.83). Conclusion: The result of the present study implies that common genetic and potential environmental factors among family members may lead to SLE, rheumatoid arthritis, and autoimmune diseases.

Original languageEnglish
Pages (from-to)466-469
Number of pages4
JournalInternational Medical Journal
Volume23
Issue number5
Publication statusPublished - Jan 1 2016

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Systemic Lupus Erythematosus
Siblings
Parents
Autoimmune Diseases
Rheumatoid Arthritis
Medical History Taking
Collagen Diseases
Drinking
Case-Control Studies
Volunteers
Logistic Models
Smoking

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Influence of medical history in parents or siblings on the development of systemic lupus erythematosus among Japanese females. / Kyushu Sapporo SLE (KYSS) Study Group.

In: International Medical Journal, Vol. 23, No. 5, 01.01.2016, p. 466-469.

Research output: Contribution to journalArticle

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title = "Influence of medical history in parents or siblings on the development of systemic lupus erythematosus among Japanese females",
abstract = "Objective: To examine the influence of medical history in parents or siblings on the development of systemic lupus erythematosus (SLE) among Japanese females. Methods: 160 female SLE patients and 660 female volunteers were studied in a case-control study. Unconditional logistic regression was used to compute OR and 95{\%} CI, with adjustment for smoking, drinking, age and region. Results: The present study demonstrated that the risk of SLE was positively associated with family histories (i.e., medical histories in parents or siblings) of SLE (OR = 5.38, 95{\%}CI = 1.43-20.20), rheumatoid arthritis (OR = 2.54, 95{\%}CI = 1.08-5.96), collagen diseases (OR = 3.48, 95{\%}CI = 1.87-6.48) and autoimmune diseases (OR = 5.25, 95{\%}CI = 1.64-16.83). Conclusion: The result of the present study implies that common genetic and potential environmental factors among family members may lead to SLE, rheumatoid arthritis, and autoimmune diseases.",
author = "{Kyushu Sapporo SLE (KYSS) Study Group} and Yoshifumi Tada and Masakazu Washio and Takahiko Horiuchi and Takahiko Horiuchi and Chikako Kiyohara and Gen Kobashi and Yuichiro Ide and Tatsuya Atsumi and Toyoko Asami and Saburo Ide and Hiroko Kodama and Koichi Akashi and Koichi Akashi and Hiroshi Tsukamoto and Takao Hotokebuchi and Kohei Nagasawa and Osamu Ushiyama and Mitsuru Mori and Asae Oura and Yasuhisa Sinomura and Hiromu Suzuki and Motohisa Yamamoto and Takashi Abe and Hisato Tanaka and Tetsuya Horita and Shinsuke Yasuda and Norihiko Nogami and Kazushi Okamoto and Naomasa Sakamoto and Satoshi Sasaki and Yoshihiro Miyake and Tetsuji Yokoyama and Masayo Oumi and Yoshio Hirota and Yutaka Inaba and Masaki Nagai",
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T1 - Influence of medical history in parents or siblings on the development of systemic lupus erythematosus among Japanese females

AU - Kyushu Sapporo SLE (KYSS) Study Group

AU - Tada, Yoshifumi

AU - Washio, Masakazu

AU - Horiuchi, Takahiko

AU - Horiuchi, Takahiko

AU - Kiyohara, Chikako

AU - Kobashi, Gen

AU - Ide, Yuichiro

AU - Atsumi, Tatsuya

AU - Asami, Toyoko

AU - Ide, Saburo

AU - Kodama, Hiroko

AU - Akashi, Koichi

AU - Akashi, Koichi

AU - Tsukamoto, Hiroshi

AU - Hotokebuchi, Takao

AU - Nagasawa, Kohei

AU - Ushiyama, Osamu

AU - Mori, Mitsuru

AU - Oura, Asae

AU - Sinomura, Yasuhisa

AU - Suzuki, Hiromu

AU - Yamamoto, Motohisa

AU - Abe, Takashi

AU - Tanaka, Hisato

AU - Horita, Tetsuya

AU - Yasuda, Shinsuke

AU - Nogami, Norihiko

AU - Okamoto, Kazushi

AU - Sakamoto, Naomasa

AU - Sasaki, Satoshi

AU - Miyake, Yoshihiro

AU - Yokoyama, Tetsuji

AU - Oumi, Masayo

AU - Hirota, Yoshio

AU - Inaba, Yutaka

AU - Nagai, Masaki

PY - 2016/1/1

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N2 - Objective: To examine the influence of medical history in parents or siblings on the development of systemic lupus erythematosus (SLE) among Japanese females. Methods: 160 female SLE patients and 660 female volunteers were studied in a case-control study. Unconditional logistic regression was used to compute OR and 95% CI, with adjustment for smoking, drinking, age and region. Results: The present study demonstrated that the risk of SLE was positively associated with family histories (i.e., medical histories in parents or siblings) of SLE (OR = 5.38, 95%CI = 1.43-20.20), rheumatoid arthritis (OR = 2.54, 95%CI = 1.08-5.96), collagen diseases (OR = 3.48, 95%CI = 1.87-6.48) and autoimmune diseases (OR = 5.25, 95%CI = 1.64-16.83). Conclusion: The result of the present study implies that common genetic and potential environmental factors among family members may lead to SLE, rheumatoid arthritis, and autoimmune diseases.

AB - Objective: To examine the influence of medical history in parents or siblings on the development of systemic lupus erythematosus (SLE) among Japanese females. Methods: 160 female SLE patients and 660 female volunteers were studied in a case-control study. Unconditional logistic regression was used to compute OR and 95% CI, with adjustment for smoking, drinking, age and region. Results: The present study demonstrated that the risk of SLE was positively associated with family histories (i.e., medical histories in parents or siblings) of SLE (OR = 5.38, 95%CI = 1.43-20.20), rheumatoid arthritis (OR = 2.54, 95%CI = 1.08-5.96), collagen diseases (OR = 3.48, 95%CI = 1.87-6.48) and autoimmune diseases (OR = 5.25, 95%CI = 1.64-16.83). Conclusion: The result of the present study implies that common genetic and potential environmental factors among family members may lead to SLE, rheumatoid arthritis, and autoimmune diseases.

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JO - International Medical Journal

JF - International Medical Journal

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