TY - JOUR
T1 - Influence of pH and ion components in the liquid phase on the setting reaction of carbonate apatite granules
AU - Tsuchiya, Akira
AU - Freitas, Pery Pinheiro
AU - Nagashima, Nozomi
AU - Ishikawa, Kunio
N1 - Funding Information:
This work was supported by AMED under Grant Number JP18im0210810 and JSPS KAKENHI Grant Number JP17K17177.
Publisher Copyright:
© 2022, Japanese Society for Dental Materials and Devices. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Carbonate apatite (CO3Ap) is an inorganic component of bone and replaces by natural bone after implantation into the bone defect. Because of this unique characteristic, CO3Ap granules have been used in the dental field. However, washing out of granules from the bone defect area is an issue. The aim of this study was to set CO3Ap granules by mixing CO3Ap granules with acidic phosphate solutions and evaluate the influence of the pH and ion components of the solutions. When Na+ was the counter ion, the amount of precipitated dicalcium phosphate dihydrate (DCPD) was small and the setting ability disappeared with increasing pH of the solutions. Alternatively, when the counter ion was Ca2+, the amount of precipitated DCPD was high and the setting ability was observed even at high pH. These results suggest the presence of Ca2+ in the acidic phosphate solution is a key for fabricating CO3Ap granular cement.
AB - Carbonate apatite (CO3Ap) is an inorganic component of bone and replaces by natural bone after implantation into the bone defect. Because of this unique characteristic, CO3Ap granules have been used in the dental field. However, washing out of granules from the bone defect area is an issue. The aim of this study was to set CO3Ap granules by mixing CO3Ap granules with acidic phosphate solutions and evaluate the influence of the pH and ion components of the solutions. When Na+ was the counter ion, the amount of precipitated dicalcium phosphate dihydrate (DCPD) was small and the setting ability disappeared with increasing pH of the solutions. Alternatively, when the counter ion was Ca2+, the amount of precipitated DCPD was high and the setting ability was observed even at high pH. These results suggest the presence of Ca2+ in the acidic phosphate solution is a key for fabricating CO3Ap granular cement.
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U2 - 10.4012/dmj.2021-211
DO - 10.4012/dmj.2021-211
M3 - Article
C2 - 34690229
AN - SCOPUS:85128161145
SN - 0287-4547
VL - 41
SP - 209
EP - 213
JO - Dental Materials Journal
JF - Dental Materials Journal
IS - 2
M1 - dmj/2021-211
ER -