Influence of substratum surface morphologies on the structure of extracellular matrix on a honeycomb film

Sadaaki Yamamoto; Hiroshi Sunami; Masaru Tanaka; Yasutaka Matsuo; Kuniharu Ijiro; Shigeko Yamashita; Yuka Morita; Masatsugu Shimomura

Influence of substratum surface morphologies on the structure of extracellular matrix on a honeycomb film

Sadaaki Yamamoto, Hiroshi Sunami, Masaru Tanaka, Yasutaka Matsuo, Kuniharu Ijiro, Shigeko Yamashita, Yuka Morita, Masatsugu Shimomura

Research output: Contribution to conference › Paper › peer-review

Abstract

The substratum surface morphology plays vital roles in cellular behavior such as adhesion, spreading, migration, proliferation and differentiation We investigated here the structure of a cellular adhesive protein, fibronectin (Fn) adsorbed on both spin-coated films (flat film) and honeycomb pattern films made of poly-ε-caprolactone by using atomic force microscope and confocal laser scanning microscope in relation to the role of the substratum surface morphology in cellular behavior. Although the adsorption saturated at mono-layer adsorption level on both substrates, the structure was inhomogeneous and depend on the surface morphology of substrates: Fn formed fibril-like aggregates on the flat films. Contrary, they adsorbed around the pores on the honeycomb films.

Original language	English
Number of pages	1
Publication status	Published - Dec 1 2005
Externally published	Yes
Event	54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: May 25 2005 → May 27 2005

Other

Other	54th SPSJ Annual Meeting 2005
Country	Japan
City	Yokohama
Period	5/25/05 → 5/27/05

All Science Journal Classification (ASJC) codes

Engineering(all)

Access to Document

Fingerprint Dive into the research topics of 'Influence of substratum surface morphologies on the structure of extracellular matrix on a honeycomb film'. Together they form a unique fingerprint.

Cite this

Influence of substratum surface morphologies on the structure of extracellular matrix on a honeycomb film. / Yamamoto, Sadaaki; Sunami, Hiroshi; Tanaka, Masaru; Matsuo, Yasutaka; Ijiro, Kuniharu; Yamashita, Shigeko; Morita, Yuka; Shimomura, Masatsugu.

2005. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.

Research output: Contribution to conference › Paper › peer-review

@conference{6c54ba13097d4d47bdcc042862ebd5f4,

title = "Influence of substratum surface morphologies on the structure of extracellular matrix on a honeycomb film",

abstract = "The substratum surface morphology plays vital roles in cellular behavior such as adhesion, spreading, migration, proliferation and differentiation We investigated here the structure of a cellular adhesive protein, fibronectin (Fn) adsorbed on both spin-coated films (flat film) and honeycomb pattern films made of poly-ε-caprolactone by using atomic force microscope and confocal laser scanning microscope in relation to the role of the substratum surface morphology in cellular behavior. Although the adsorption saturated at mono-layer adsorption level on both substrates, the structure was inhomogeneous and depend on the surface morphology of substrates: Fn formed fibril-like aggregates on the flat films. Contrary, they adsorbed around the pores on the honeycomb films.",

author = "Sadaaki Yamamoto and Hiroshi Sunami and Masaru Tanaka and Yasutaka Matsuo and Kuniharu Ijiro and Shigeko Yamashita and Yuka Morita and Masatsugu Shimomura",

year = "2005",

month = dec,

day = "1",

language = "English",

note = "54th SPSJ Annual Meeting 2005 ; Conference date: 25-05-2005 Through 27-05-2005",

}

TY - CONF

T1 - Influence of substratum surface morphologies on the structure of extracellular matrix on a honeycomb film

AU - Yamamoto, Sadaaki

AU - Sunami, Hiroshi

AU - Tanaka, Masaru

AU - Matsuo, Yasutaka

AU - Ijiro, Kuniharu

AU - Yamashita, Shigeko

AU - Morita, Yuka

AU - Shimomura, Masatsugu

PY - 2005/12/1

Y1 - 2005/12/1

N2 - The substratum surface morphology plays vital roles in cellular behavior such as adhesion, spreading, migration, proliferation and differentiation We investigated here the structure of a cellular adhesive protein, fibronectin (Fn) adsorbed on both spin-coated films (flat film) and honeycomb pattern films made of poly-ε-caprolactone by using atomic force microscope and confocal laser scanning microscope in relation to the role of the substratum surface morphology in cellular behavior. Although the adsorption saturated at mono-layer adsorption level on both substrates, the structure was inhomogeneous and depend on the surface morphology of substrates: Fn formed fibril-like aggregates on the flat films. Contrary, they adsorbed around the pores on the honeycomb films.

AB - The substratum surface morphology plays vital roles in cellular behavior such as adhesion, spreading, migration, proliferation and differentiation We investigated here the structure of a cellular adhesive protein, fibronectin (Fn) adsorbed on both spin-coated films (flat film) and honeycomb pattern films made of poly-ε-caprolactone by using atomic force microscope and confocal laser scanning microscope in relation to the role of the substratum surface morphology in cellular behavior. Although the adsorption saturated at mono-layer adsorption level on both substrates, the structure was inhomogeneous and depend on the surface morphology of substrates: Fn formed fibril-like aggregates on the flat films. Contrary, they adsorbed around the pores on the honeycomb films.

UR - http://www.scopus.com/inward/record.url?scp=33645641898&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645641898&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33645641898

T2 - 54th SPSJ Annual Meeting 2005

Y2 - 25 May 2005 through 27 May 2005

ER -