Influenza in three patients with human immunodeficiency virus infection

Shigeki Nabeshima, Iwao Ariyama, Yong Chong, Kohei Hirotsu, Kyoji Kakuda, Jun Hayashi, Seizaburo Kashiwagi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Three Japanese outpatients with human immunodeficiency virus (HIV) infection on anti-retroviral therapy showed evidence of influenza in January 1999. CD4+T cell counts of these patients prior to the diagnosis of influenza were 72, 248, and 152/mm3, and HIV RNA levels were 19,953, 1,259, and 1,585 copies/ml, respectively. Fever continued 4 to 5 days with no severe complications. One patient showed post-influenzal bronchitis which was effectively treated by antibiotics. None of these patients showed increased serum HIV RNA levels during and after influenza, however, in one patient, a transient reduction of CD4+ and CD8+ cells was seen during the active phase of influenza. Although symptoms of influenza in HIV carriers are generally mild and similar to those in healthy adults, careful follow-up is needed as symptoms of influenza in some HIV-infected patients can be prolonged and serious.

Original languageEnglish
Pages (from-to)592-597
Number of pages6
JournalInternal Medicine
Issue number7
Publication statusPublished - Jul 2000

All Science Journal Classification (ASJC) codes

  • Internal Medicine


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