Influenza-induced rhabdomyolysis after autologous peripheral blood stem cell transplantation for malignant lymphoma

Masatsugu Nozoe; Tadafumi Iino; Koji Nagafuji; Toshihiro Miyamoto; Hiroyuki Ito; Hisashi Gondo; Mine Harada

doi:10.2169/internalmedicine.42.1127

Influenza-induced rhabdomyolysis after autologous peripheral blood stem cell transplantation for malignant lymphoma

Masatsugu Nozoe, Tadafumi Iino, Koji Nagafuji, Toshihiro Miyamoto, Hiroyuki Ito, Hisashi Gondo, Mine Harada

Internal Medicine

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

We report influenza-induced rhabodmyolysis and congestive heart failure after high-dose therapy and hematopoietic stem cell transplantation for malignant lymphoma. Four months after autologous peripheral blood stem cell transplantation for the treatment of malignant lymphoma, a 65-year-old Japanese man developed acute congestive heart failure requiring artificial ventilation and rahbdomyolysis. Since influenza A virus was documented from his nasal cavity, he was diagnosed as rhabdomyolysis and congestive heart failure induced by influenza A infection. Neuraminidase inhibitor (oseltamivir 150 mg/day for 5 days) was administrated, and heart failure and respiratory status were improved. Our experience suggests that early treatment with neuraminidase inhibitor may improve the clinical outcome of influenza-induced rhabdomyolysis and congestive heart failure.

Original language	English
Pages (from-to)	1127-1130
Number of pages	4
Journal	Internal Medicine
Volume	42
Issue number	11
DOIs	https://doi.org/10.2169/internalmedicine.42.1127
Publication status	Published - Nov 2003

All Science Journal Classification (ASJC) codes

Internal Medicine

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10.2169/internalmedicine.42.1127

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title = "Influenza-induced rhabdomyolysis after autologous peripheral blood stem cell transplantation for malignant lymphoma",

abstract = "We report influenza-induced rhabodmyolysis and congestive heart failure after high-dose therapy and hematopoietic stem cell transplantation for malignant lymphoma. Four months after autologous peripheral blood stem cell transplantation for the treatment of malignant lymphoma, a 65-year-old Japanese man developed acute congestive heart failure requiring artificial ventilation and rahbdomyolysis. Since influenza A virus was documented from his nasal cavity, he was diagnosed as rhabdomyolysis and congestive heart failure induced by influenza A infection. Neuraminidase inhibitor (oseltamivir 150 mg/day for 5 days) was administrated, and heart failure and respiratory status were improved. Our experience suggests that early treatment with neuraminidase inhibitor may improve the clinical outcome of influenza-induced rhabdomyolysis and congestive heart failure.",

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AU - Nozoe, Masatsugu

AU - Iino, Tadafumi

AU - Nagafuji, Koji

AU - Miyamoto, Toshihiro

AU - Ito, Hiroyuki

AU - Gondo, Hisashi

AU - Harada, Mine

PY - 2003/11

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N2 - We report influenza-induced rhabodmyolysis and congestive heart failure after high-dose therapy and hematopoietic stem cell transplantation for malignant lymphoma. Four months after autologous peripheral blood stem cell transplantation for the treatment of malignant lymphoma, a 65-year-old Japanese man developed acute congestive heart failure requiring artificial ventilation and rahbdomyolysis. Since influenza A virus was documented from his nasal cavity, he was diagnosed as rhabdomyolysis and congestive heart failure induced by influenza A infection. Neuraminidase inhibitor (oseltamivir 150 mg/day for 5 days) was administrated, and heart failure and respiratory status were improved. Our experience suggests that early treatment with neuraminidase inhibitor may improve the clinical outcome of influenza-induced rhabdomyolysis and congestive heart failure.

AB - We report influenza-induced rhabodmyolysis and congestive heart failure after high-dose therapy and hematopoietic stem cell transplantation for malignant lymphoma. Four months after autologous peripheral blood stem cell transplantation for the treatment of malignant lymphoma, a 65-year-old Japanese man developed acute congestive heart failure requiring artificial ventilation and rahbdomyolysis. Since influenza A virus was documented from his nasal cavity, he was diagnosed as rhabdomyolysis and congestive heart failure induced by influenza A infection. Neuraminidase inhibitor (oseltamivir 150 mg/day for 5 days) was administrated, and heart failure and respiratory status were improved. Our experience suggests that early treatment with neuraminidase inhibitor may improve the clinical outcome of influenza-induced rhabdomyolysis and congestive heart failure.

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Influenza-induced rhabdomyolysis after autologous peripheral blood stem cell transplantation for malignant lymphoma

Abstract

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