Influenza-induced rhabdomyolysis after autologous peripheral blood stem cell transplantation for malignant lymphoma

Masatsugu Nozoe, Tadafumi Iino, Koji Nagafuji, Toshihiro Miyamoto, Hiroyuki Ito, Hisashi Gondo, Mine Harada

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Abstract

We report influenza-induced rhabodmyolysis and congestive heart failure after high-dose therapy and hematopoietic stem cell transplantation for malignant lymphoma. Four months after autologous peripheral blood stem cell transplantation for the treatment of malignant lymphoma, a 65-year-old Japanese man developed acute congestive heart failure requiring artificial ventilation and rahbdomyolysis. Since influenza A virus was documented from his nasal cavity, he was diagnosed as rhabdomyolysis and congestive heart failure induced by influenza A infection. Neuraminidase inhibitor (oseltamivir 150 mg/day for 5 days) was administrated, and heart failure and respiratory status were improved. Our experience suggests that early treatment with neuraminidase inhibitor may improve the clinical outcome of influenza-induced rhabdomyolysis and congestive heart failure.

Original languageEnglish
Pages (from-to)1127-1130
Number of pages4
JournalInternal Medicine
Volume42
Issue number11
DOIs
Publication statusPublished - Nov 2003

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All Science Journal Classification (ASJC) codes

  • Internal Medicine

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