Inhibitory effect of a SALMFamide neuropeptide on secretion of gonad-stimulating substance from radial nerves in the starfish Asterina pectinifera

Masatoshi Mita, Hiroko Oka, Michael C. Thorndyke, Yasushi Shibata, Michiyasu Yoshikuni, Yoshitaka Nagahama

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In starfish, the peptide hormone gonad-stimulating substance (GSS) secreted from nervous tissue stimulates oocyte maturation to induce 1-methyladenine (1-MeAde) production by ovarian follicle cells. The SALMFamide family is also known to an echinoderm neuropeptide. The present study examined effect of SALMFamide 1 (S1) on oocyte maturation of starfish Asterina pectinifera. Unlike GSS, S1 did not induce spawning in starfish ovary. In contrast, S1 was found to inhibit GSS secretion from radial nerves by treatment with high K+ concentration. Fifty percent inhibition was obtained by 0.1 mM S1. S1 did not have any effect on GSS- and 1-MeAde-induced oocyte maturation. Following incubation with a S1 antibody and subsequently with rhodamine-conjugated second antibody, neural networks were observed in ovaries. The networks were restricted mainly to their surface with little evidence of immunoreactivity inside the basement membranes. This indicates that neural networks are distributed in the ovarian wall. The result further suggests that S1 plays a role in oocyte maturation to regulate GSS secretion from the nervous system.

Original languageEnglish
Pages (from-to)299-303
Number of pages5
JournalZoological science
Volume21
Issue number3
DOIs
Publication statusPublished - Mar 1 2004
Externally publishedYes

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Asterina pectinifera
Asteroidea
neuropeptides
gonads
nerve tissue
secretion
oocytes
neural networks
peptide hormones
antibodies
ovarian follicles
basement membrane
Echinodermata
nervous system
spawning

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology

Cite this

Inhibitory effect of a SALMFamide neuropeptide on secretion of gonad-stimulating substance from radial nerves in the starfish Asterina pectinifera. / Mita, Masatoshi; Oka, Hiroko; Thorndyke, Michael C.; Shibata, Yasushi; Yoshikuni, Michiyasu; Nagahama, Yoshitaka.

In: Zoological science, Vol. 21, No. 3, 01.03.2004, p. 299-303.

Research output: Contribution to journalArticle

Mita, Masatoshi ; Oka, Hiroko ; Thorndyke, Michael C. ; Shibata, Yasushi ; Yoshikuni, Michiyasu ; Nagahama, Yoshitaka. / Inhibitory effect of a SALMFamide neuropeptide on secretion of gonad-stimulating substance from radial nerves in the starfish Asterina pectinifera. In: Zoological science. 2004 ; Vol. 21, No. 3. pp. 299-303.
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