Insulin and glucagon responses to intravenous injections of glucose, arginine and propionate in lactating cows and growing calves

H. Sano, H. Arai, A. Takahashi, Hideyuki Takahashi, Y. Terashima

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Plasma insulin and glucagon responses to glucose, arginine and propionate injections were measured to establish indicators of the endocrine status in lactating cows and growing calves. The metabolites were intravenously injected at a dose of 0.625 mmol kg -1 and the time courses of changes in plasma insulin and glucagon concentrations were determined. Basal plasma glucagon concentrations were higher (P < 0.05) for lactating cows than for growing calves, while basal plasma insulin concentrations did not differ between animal groups. Concentrations of plasma insulin increased (P < 0.01) after glucose injection, whereas plasma glucagon concentrations decreased in both lactating cows (P < 0.05) and growing calves (P < 0.01). Plasma insulin and glucagon concentrations increased in response to arginine (P < 0.01) and propionate (P < 0.01 except insulin for lactating cows at P < 0.05) injections. Plasma insulin and glucagon responses were greater (P < 0.05) to arginine than to glucose or propionate. Plasma glucagon responses to arginine were greater (P < 0.05) for lactating cows than for growing calves. The insulin:glucagon molar ratio increased in response to the metabolite injections except following injections of arginine and propionate into lactating cows, when the ratio did not increase significantly. It is possible that in cows the enhanced responsiveness of glucagon secretion plays a role in the maintenance of lactation.

Original languageEnglish
Pages (from-to)309-314
Number of pages6
JournalCanadian Journal of Animal Science
Volume79
Issue number3
DOIs
Publication statusPublished - Jan 1 1999
Externally publishedYes

Fingerprint

glucagon
Propionates
Glucagon
propionates
intravenous injection
Intravenous Injections
arginine
Arginine
insulin
calves
Insulin
Glucose
cows
glucose
injection
Injections
metabolites
Lactation
lactation
Maintenance

All Science Journal Classification (ASJC) codes

  • Food Animals
  • Animal Science and Zoology

Cite this

Insulin and glucagon responses to intravenous injections of glucose, arginine and propionate in lactating cows and growing calves. / Sano, H.; Arai, H.; Takahashi, A.; Takahashi, Hideyuki; Terashima, Y.

In: Canadian Journal of Animal Science, Vol. 79, No. 3, 01.01.1999, p. 309-314.

Research output: Contribution to journalArticle

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