Interaction between sulfated glycoconjugate polymer and alzheimer amyloid

Yoshiko Miura, Kikuko Yasuda, Kiyofumi Yamamoto, Syunshuke Onogi, Yoshihiro Nishida, Kazukiyo Kobayashi

Research output: Contribution to conferencePaper

Abstract

The interaction between glycopolymer and Aβ was analyzed. Glycopolymer with sulfated sugar inhibited the aggregation of Aβ. The inhibition effect was not observed with polyacrylamide and polyvalent GlcNAc. The conformation of Aβ with glycopolymer was depending on the glycopolymer structure and sugar contents. These results showed that the glycopolymer could be the Aβ inihibitor.

Original languageEnglish
Number of pages1
Publication statusPublished - Oct 19 2006
Externally publishedYes
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: May 24 2006May 26 2006

Other

Other55th SPSJ Annual Meeting
CountryJapan
CityNagoya
Period5/24/065/26/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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  • Cite this

    Miura, Y., Yasuda, K., Yamamoto, K., Onogi, S., Nishida, Y., & Kobayashi, K. (2006). Interaction between sulfated glycoconjugate polymer and alzheimer amyloid. Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan.