International photographic classification and grading system for myopic maculopathy

Kyoko Ohno-Matsui, Ryo Kawasaki, Jost B. Jonas, Chui Ming Gemmy Cheung, Seang Mei Saw, Virginie J.M. Verhoeven, Caroline C.W. Klaver, Muka Moriyama, Kosei Shinohara, Yumiko Kawasaki, Mai Yamazaki, Stacy Meuer, Tatsuro Ishibashi, Miho Yasuda, Hidetoshi Yamashita, Akira Sugano, Jie Jin Wang, Paul Mitchell, Tien Yin Wong

Research output: Contribution to journalArticle

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Abstract

Purpose To develop a classification and grading system for myopic maculopathy. Design Development and evaluation of a classification system for myopic maculopathy based on observational case series. Methods A comprehensive set of myopic macular lesions was defined via literature review and through consensus meetings among retinal specialists and clinician scientists. A classification of myopic maculopathy was formulated based on fundus photographs and a modified Delphi process and consensus. Inter- and intraobserver reproducibility, assessed as agreement (%) and weighted kappa values, were evaluated. One hundred retinal photographs with myopia and myopic macular lesions were selected from case series at the High Myopia Clinic of the Tokyo Medical and Dental University, Tokyo, Japan. Results We defined 5 categories of myopic maculopathy including "no myopic retinal degenerative lesion" (Category 0), "tessellated fundus" (Category 1), "diffuse chorioretinal atrophy" (Category 2), "patchy chorioretinal atrophy" (Category 3), and "macular atrophy" (Category 4). Three additional features to supplement these categories were defined as "plus" lesions, namely, lacquer cracks, myopic choroidal neovascularization, and Fuchs spot. Posterior staphyloma was considered as a further, important sign of myopic retinopathy. The intraobserver agreement was ≥85% and the corresponding weighted kappa statistic was ≥0.6 between observations. After a brief training session, interobserver kappa statistics reached the predefined satisfactory level (≥0.4), considered as above moderate agreement. Conclusions We propose a classification system for myopic maculopathy that was found to be reproducible. Applying a uniform classification in different studies will facilitate communication and comparison of findings from clinical trials and epidemiologic studies.

Original languageEnglish
Article number9218
Pages (from-to)877-883.e7
JournalAmerican journal of ophthalmology
Volume159
Issue number5
DOIs
Publication statusPublished - May 1 2015

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Atrophy
Tokyo
Myopia
Lacquer
Choroidal Neovascularization
Epidemiologic Studies
Tooth
Japan
Clinical Trials
Clinical Studies

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Ohno-Matsui, K., Kawasaki, R., Jonas, J. B., Cheung, C. M. G., Saw, S. M., Verhoeven, V. J. M., ... Wong, T. Y. (2015). International photographic classification and grading system for myopic maculopathy. American journal of ophthalmology, 159(5), 877-883.e7. [9218]. https://doi.org/10.1016/j.ajo.2015.01.022

International photographic classification and grading system for myopic maculopathy. / Ohno-Matsui, Kyoko; Kawasaki, Ryo; Jonas, Jost B.; Cheung, Chui Ming Gemmy; Saw, Seang Mei; Verhoeven, Virginie J.M.; Klaver, Caroline C.W.; Moriyama, Muka; Shinohara, Kosei; Kawasaki, Yumiko; Yamazaki, Mai; Meuer, Stacy; Ishibashi, Tatsuro; Yasuda, Miho; Yamashita, Hidetoshi; Sugano, Akira; Wang, Jie Jin; Mitchell, Paul; Wong, Tien Yin.

In: American journal of ophthalmology, Vol. 159, No. 5, 9218, 01.05.2015, p. 877-883.e7.

Research output: Contribution to journalArticle

Ohno-Matsui, K, Kawasaki, R, Jonas, JB, Cheung, CMG, Saw, SM, Verhoeven, VJM, Klaver, CCW, Moriyama, M, Shinohara, K, Kawasaki, Y, Yamazaki, M, Meuer, S, Ishibashi, T, Yasuda, M, Yamashita, H, Sugano, A, Wang, JJ, Mitchell, P & Wong, TY 2015, 'International photographic classification and grading system for myopic maculopathy', American journal of ophthalmology, vol. 159, no. 5, 9218, pp. 877-883.e7. https://doi.org/10.1016/j.ajo.2015.01.022
Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CMG, Saw SM, Verhoeven VJM et al. International photographic classification and grading system for myopic maculopathy. American journal of ophthalmology. 2015 May 1;159(5):877-883.e7. 9218. https://doi.org/10.1016/j.ajo.2015.01.022
Ohno-Matsui, Kyoko ; Kawasaki, Ryo ; Jonas, Jost B. ; Cheung, Chui Ming Gemmy ; Saw, Seang Mei ; Verhoeven, Virginie J.M. ; Klaver, Caroline C.W. ; Moriyama, Muka ; Shinohara, Kosei ; Kawasaki, Yumiko ; Yamazaki, Mai ; Meuer, Stacy ; Ishibashi, Tatsuro ; Yasuda, Miho ; Yamashita, Hidetoshi ; Sugano, Akira ; Wang, Jie Jin ; Mitchell, Paul ; Wong, Tien Yin. / International photographic classification and grading system for myopic maculopathy. In: American journal of ophthalmology. 2015 ; Vol. 159, No. 5. pp. 877-883.e7.
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AU - Jonas, Jost B.

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AU - Saw, Seang Mei

AU - Verhoeven, Virginie J.M.

AU - Klaver, Caroline C.W.

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AU - Shinohara, Kosei

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AU - Yamazaki, Mai

AU - Meuer, Stacy

AU - Ishibashi, Tatsuro

AU - Yasuda, Miho

AU - Yamashita, Hidetoshi

AU - Sugano, Akira

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