Intimal thickening and the distribution of vasomotor nerves in the mechanically injured dog coronary artery

Tomoaki Taguchi, Yutaka Ishii, Fujio Matsubara, Kenzo Tanaka

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Intimal injury and atherosclerotic change seem to be causative factors linked to spasm of the coronary artery. Intimal thickening was produced by mechanical injury to the endothelium of the canine coronary artery and we investigated the distribution of adrenergic, cholinergic, and peptidergic nerves in the coronary arteries. Although adrenergic and cholinergic nerves were not altered in density, neuron specific enolase positive nerve fibers were increased in number in dogs killed 1 and 3 months after injury. Substance P-containing fibers were also increased at 3 months after the induced injury.

Original languageEnglish
Pages (from-to)138-146
Number of pages9
JournalExperimental and Molecular Pathology
Volume44
Issue number2
DOIs
Publication statusPublished - Apr 1986

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Clinical Biochemistry

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