Intractable otitis media with eosinophils

Importance of diagnosis and validity of treatment for hearing preservation

Takashi Nakagawa, Atsushi Matsubara, Hideki Shiratsuchi, Yasuhiro Kakazu, Torahiko Nakashima, Koji Koike, Toshiro Umezaki, Shizuo Komune

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

This study investigated hearing levels in cases of intractable otitis media with eosinophils and validated the treatment strategy. Medical charts were reviewed retrospectively. The diagnosis was made when the proportion of eosinophils in middle ear secretions exceeded 10%. Twelve patients were identified and treated with an antihistaminergic agent, leukotriene receptor antagonist and topical steroid. The air-bone conductance gap decreased significantly with the relief of subjective symptoms. Bone conduction hearing levels at 4 and 8 kHz were higher than at lower frequencies. There was a significant correlation between subjective symptom duration and bone conduction hearing level at 8 kHz, which diminished with treatment. Compared with suppurative otitis, active otitis with eosinophilia damages high-tone sensory hearing in a time-dependent manner, and antiallergic treatment prevents progression of the high-tone sensory hearing loss. We emphasize the importance of diagnosis and the validity of treatment for intractable otitis media with eosinophils.

Original languageEnglish
Pages (from-to)118-122
Number of pages5
JournalORL
Volume68
Issue number2
DOIs
Publication statusPublished - Mar 1 2006

Fingerprint

Otitis Media
Eosinophils
Hearing
Bone Conduction
Otitis
Leukotriene Antagonists
Anti-Allergic Agents
Eosinophilia
Middle Ear
Therapeutics
Hearing Loss
Steroids
Air
Bone and Bones

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Nakagawa, T., Matsubara, A., Shiratsuchi, H., Kakazu, Y., Nakashima, T., Koike, K., ... Komune, S. (2006). Intractable otitis media with eosinophils: Importance of diagnosis and validity of treatment for hearing preservation. ORL, 68(2), 118-122. https://doi.org/10.1159/000091215

Intractable otitis media with eosinophils : Importance of diagnosis and validity of treatment for hearing preservation. / Nakagawa, Takashi; Matsubara, Atsushi; Shiratsuchi, Hideki; Kakazu, Yasuhiro; Nakashima, Torahiko; Koike, Koji; Umezaki, Toshiro; Komune, Shizuo.

In: ORL, Vol. 68, No. 2, 01.03.2006, p. 118-122.

Research output: Contribution to journalArticle

Nakagawa, T, Matsubara, A, Shiratsuchi, H, Kakazu, Y, Nakashima, T, Koike, K, Umezaki, T & Komune, S 2006, 'Intractable otitis media with eosinophils: Importance of diagnosis and validity of treatment for hearing preservation', ORL, vol. 68, no. 2, pp. 118-122. https://doi.org/10.1159/000091215
Nakagawa, Takashi ; Matsubara, Atsushi ; Shiratsuchi, Hideki ; Kakazu, Yasuhiro ; Nakashima, Torahiko ; Koike, Koji ; Umezaki, Toshiro ; Komune, Shizuo. / Intractable otitis media with eosinophils : Importance of diagnosis and validity of treatment for hearing preservation. In: ORL. 2006 ; Vol. 68, No. 2. pp. 118-122.
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