Intrahepatic cholangiocarcinoma after the Fontan procedure

Yuichi Shibui, Kenichi Kouhashi, Ichiro Sakamoto, Kenichiro Yamamura, Yoshinao Oda

Research output: Contribution to journalArticle

Abstract

A long duration of Fontan circulation can cause fibrosis, cirrhosis of the liver and liver cancer. There have been some reports of hepatocellular carcinoma occurring after the Fontan procedure (FP), and we encountered a case of intrahepatic cholangiocarcinoma (ICC) after the FP. We herein report the case of 33-year-old man who developed ICC after receiving the FP. At five years of age, the patient underwent the original FP. At 16 years of age, he received total cavopulmonary connection conversion. Sixteen years later, he suffered right heart failure. Thereafter his symptoms showed repeated exacerbation and remission. One year later, he was admitted to the hospital due to the aggravation of congestive heart failure symptoms. He developed contrast nephropathy, and his renal function rapidly weakened. Computed tomography revealed multiple mass lesions in the liver. He ultimately died four months after his admission. An autopsy revealed the hepatic tumor to be ICC. Patients who have undergone the FP need to undergo a checkup with ultrasound on a regular basis.

LanguageEnglish
Pages15-19
Number of pages5
JournalHuman Pathology: Case Reports
Volume15
DOIs
Publication statusPublished - Mar 1 2019

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Fontan Procedure
Cholangiocarcinoma
Liver Cirrhosis
Heart Failure
Liver
Liver Neoplasms
Hepatocellular Carcinoma
Autopsy
Tomography
Kidney
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

Intrahepatic cholangiocarcinoma after the Fontan procedure. / Shibui, Yuichi; Kouhashi, Kenichi; Sakamoto, Ichiro; Yamamura, Kenichiro; Oda, Yoshinao.

In: Human Pathology: Case Reports, Vol. 15, 01.03.2019, p. 15-19.

Research output: Contribution to journalArticle

Shibui, Yuichi ; Kouhashi, Kenichi ; Sakamoto, Ichiro ; Yamamura, Kenichiro ; Oda, Yoshinao. / Intrahepatic cholangiocarcinoma after the Fontan procedure. In: Human Pathology: Case Reports. 2019 ; Vol. 15. pp. 15-19.
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