Abstract
We present a case of a pregnant woman with hereditary antithrombin III deficiency and deep vein thrombosis of the left lower extremity managed by perinatal unfractionated heparin injection with antithrombin III replacement as well as by intrapartum placement of a temporary inferior vena cava filter. A massive thrombus of the right common iliac vein occurred during the intrapartum period despite antithrombin III replacement. An inserted filter could prevent fatal pulmonary embolism in this patient. Hereditary antithrombin III deficiency increases risk of thrombosis during pregnancy. However, discussion on intrapartum management, when anticoagulants are contraindicated due to possible hemorrhage, is minimal. Our experience suggests that thrombosis can occur and develop during the intrapartum period in an antithrombin III deficient woman despite antithrombin III replacement. It may be advisable to manage deliveries with temporary inferior vena cava filters to prevent fatal pulmonary embolism.
| Original language | English |
|---|---|
| Pages (from-to) | 95-99 |
| Number of pages | 5 |
| Journal | Journal of Obstetrics and Gynaecology Research |
| Volume | 34 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 1 2008 |
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All Science Journal Classification (ASJC) codes
- Obstetrics and Gynaecology
Cite this
Intrapartum placement of an inferior vena cava filter for a woman with hereditary antithrombin III deficiency : Its role in the prevention of fatal pulmonary embolism. / Hidaka, Nobuhiro; Hachisuga, Masahiro; Tsukimori, Kiyomi; Onohara, Toshihiro; Maehara, Yoshihiko; Wake, Norio.
In: Journal of Obstetrics and Gynaecology Research, Vol. 34, No. 1, 01.02.2008, p. 95-99.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intrapartum placement of an inferior vena cava filter for a woman with hereditary antithrombin III deficiency
T2 - Its role in the prevention of fatal pulmonary embolism
AU - Hidaka, Nobuhiro
AU - Hachisuga, Masahiro
AU - Tsukimori, Kiyomi
AU - Onohara, Toshihiro
AU - Maehara, Yoshihiko
AU - Wake, Norio
PY - 2008/2/1
Y1 - 2008/2/1
N2 - We present a case of a pregnant woman with hereditary antithrombin III deficiency and deep vein thrombosis of the left lower extremity managed by perinatal unfractionated heparin injection with antithrombin III replacement as well as by intrapartum placement of a temporary inferior vena cava filter. A massive thrombus of the right common iliac vein occurred during the intrapartum period despite antithrombin III replacement. An inserted filter could prevent fatal pulmonary embolism in this patient. Hereditary antithrombin III deficiency increases risk of thrombosis during pregnancy. However, discussion on intrapartum management, when anticoagulants are contraindicated due to possible hemorrhage, is minimal. Our experience suggests that thrombosis can occur and develop during the intrapartum period in an antithrombin III deficient woman despite antithrombin III replacement. It may be advisable to manage deliveries with temporary inferior vena cava filters to prevent fatal pulmonary embolism.
AB - We present a case of a pregnant woman with hereditary antithrombin III deficiency and deep vein thrombosis of the left lower extremity managed by perinatal unfractionated heparin injection with antithrombin III replacement as well as by intrapartum placement of a temporary inferior vena cava filter. A massive thrombus of the right common iliac vein occurred during the intrapartum period despite antithrombin III replacement. An inserted filter could prevent fatal pulmonary embolism in this patient. Hereditary antithrombin III deficiency increases risk of thrombosis during pregnancy. However, discussion on intrapartum management, when anticoagulants are contraindicated due to possible hemorrhage, is minimal. Our experience suggests that thrombosis can occur and develop during the intrapartum period in an antithrombin III deficient woman despite antithrombin III replacement. It may be advisable to manage deliveries with temporary inferior vena cava filters to prevent fatal pulmonary embolism.
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U2 - 10.1111/j.1447-0756.2007.00708.x
DO - 10.1111/j.1447-0756.2007.00708.x
M3 - Article
C2 - 18226138
AN - SCOPUS:38449121700
VL - 34
SP - 95
EP - 99
JO - Journal of Obstetrics and Gynaecology Research
JF - Journal of Obstetrics and Gynaecology Research
SN - 1341-8076
IS - 1
ER -