Intrathecal infusion of microglia cells

Takahiro Masuda; Makoto Tsuda; Hidetoshi Tozaki-Saitoh; Kazuhide Inoue

doi:10.1007/978-1-62703-520-0_25

Intrathecal infusion of microglia cells

Takahiro Masuda, Makoto Tsuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Abstract

Spinal microglia have been implicated in the pathogenesis of neuropathic pain after peripheral nerve injury concomitant with diseases such as diabetes and cancer. To reveal the etiological roles of microglia in behavioral pain hypersensitivity or neuronal excitability, technical approaches have been used. Here, we describe a technique for intrathecal transfer of cultured microglial cells through a catheter surgically implanted into the spinal subarachnoid space.

Original language	English
Title of host publication	Microglia
Subtitle of host publication	Methods and Protocols
Pages	291-294
Number of pages	4
DOIs	https://doi.org/10.1007/978-1-62703-520-0_25
Publication status	Published - Jul 18 2013

Publication series

Name	Methods in Molecular Biology
Volume	1041
ISSN (Print)	1064-3745

All Science Journal Classification (ASJC) codes

Molecular Biology
Genetics

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abstract = "Spinal microglia have been implicated in the pathogenesis of neuropathic pain after peripheral nerve injury concomitant with diseases such as diabetes and cancer. To reveal the etiological roles of microglia in behavioral pain hypersensitivity or neuronal excitability, technical approaches have been used. Here, we describe a technique for intrathecal transfer of cultured microglial cells through a catheter surgically implanted into the spinal subarachnoid space.",

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