Spinal microglia have been implicated in the pathogenesis of neuropathic pain after peripheral nerve injury concomitant with diseases such as diabetes and cancer. To reveal the etiological roles of microglia in behavioral pain hypersensitivity or neuronal excitability, technical approaches have been used. Here, we describe a technique for intrathecal transfer of cultured microglial cells through a catheter surgically implanted into the spinal subarachnoid space.
|Title of host publication||Microglia|
|Subtitle of host publication||Methods and Protocols|
|Number of pages||4|
|Publication status||Published - Jul 18 2013|
|Name||Methods in Molecular Biology|
All Science Journal Classification (ASJC) codes
- Molecular Biology