Intravoxel incoherent motion magnetic resonance imaging findings in the acute phase of MELAS: A case report

Ryuji Uehara, Koji Yamashita, Akio Hiwatashi, Osamu Togao, Kazufumi Kikuchi, Jun Yokoyama, Dai Matsuse, Takashi Yoshiura, Hiroshi Honda

Research output: Contribution to journalArticle

Abstract

Objective: We report the clinical application of intravoxel incoherent motion (IVIM) magnetic resonance (MR) imaging to diagnose a case of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) in the acute phase. Results: On IVIM MR Images of this patient, higher perfusion (f) and diffusion (D) values in the left occipital and temporal lobes were found compared to the contralateral areas. Conclusion: These findings imply a breakdown of autoregulation with hyperperfusion and vasogenic edema during the acute phase of MELAS, as described in previous reports. IVIM imaging is a valuable, noninvasive tool that simultaneously quantifies perfusion and diffusion parameters.

Original languageEnglish
Pages (from-to)798-800
Number of pages3
JournalBrain and Behavior
Volume4
Issue number6
DOIs
Publication statusPublished - Nov 1 2014

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Lactic Acidosis
Brain Diseases
Muscular Diseases
Stroke
Magnetic Resonance Imaging
Perfusion
MELAS Syndrome
Occipital Lobe
Temporal Lobe
Edema
Homeostasis
Magnetic Resonance Spectroscopy

All Science Journal Classification (ASJC) codes

  • Behavioral Neuroscience

Cite this

Intravoxel incoherent motion magnetic resonance imaging findings in the acute phase of MELAS : A case report. / Uehara, Ryuji; Yamashita, Koji; Hiwatashi, Akio; Togao, Osamu; Kikuchi, Kazufumi; Yokoyama, Jun; Matsuse, Dai; Yoshiura, Takashi; Honda, Hiroshi.

In: Brain and Behavior, Vol. 4, No. 6, 01.11.2014, p. 798-800.

Research output: Contribution to journalArticle

Uehara, Ryuji ; Yamashita, Koji ; Hiwatashi, Akio ; Togao, Osamu ; Kikuchi, Kazufumi ; Yokoyama, Jun ; Matsuse, Dai ; Yoshiura, Takashi ; Honda, Hiroshi. / Intravoxel incoherent motion magnetic resonance imaging findings in the acute phase of MELAS : A case report. In: Brain and Behavior. 2014 ; Vol. 4, No. 6. pp. 798-800.
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