Inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia: A case report of 9-month-old infant

Shoichi Ohga, E. Ishii, K. Fujioka, K. Ueda

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Recently, it has been reported that many patients with acute myelomonocytic leukemia showed rearrangements of chromosome 16 in leukemic cells and abnormal eosinophils in bone marrow. Among the reported cases, the youngest was a 14-month-old male infant. We report a 9-month-old female infant with acute myelomonocytic leukemia with leukemic cells having a pericentric inversion of chromosome 16, inv (16) (p13q22), and for whom abnormal immature eosinophils with basophilic granules were observed in the bone marrow. The patient achieved complete remission after several courses of combination chemotherapy, and neither abnormal marrow eosinophils nor chromosomal abnormalities have been founds after nine months.

Original languageEnglish
Pages (from-to)114-118
Number of pages5
JournalActa Haematologica Japonica
Volume50
Issue number1
Publication statusPublished - Jan 1 1987

Fingerprint

Leukemia, Myelomonocytic, Acute
Chromosomes, Human, Pair 16
Eosinophils
Bone Marrow
Combination Drug Therapy
Chromosome Aberrations

All Science Journal Classification (ASJC) codes

  • Hematology

Cite this

Inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia : A case report of 9-month-old infant. / Ohga, Shoichi; Ishii, E.; Fujioka, K.; Ueda, K.

In: Acta Haematologica Japonica, Vol. 50, No. 1, 01.01.1987, p. 114-118.

Research output: Contribution to journalArticle

@article{b3cbcd3164944634998838775197d1a0,
title = "Inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia: A case report of 9-month-old infant",
abstract = "Recently, it has been reported that many patients with acute myelomonocytic leukemia showed rearrangements of chromosome 16 in leukemic cells and abnormal eosinophils in bone marrow. Among the reported cases, the youngest was a 14-month-old male infant. We report a 9-month-old female infant with acute myelomonocytic leukemia with leukemic cells having a pericentric inversion of chromosome 16, inv (16) (p13q22), and for whom abnormal immature eosinophils with basophilic granules were observed in the bone marrow. The patient achieved complete remission after several courses of combination chemotherapy, and neither abnormal marrow eosinophils nor chromosomal abnormalities have been founds after nine months.",
author = "Shoichi Ohga and E. Ishii and K. Fujioka and K. Ueda",
year = "1987",
month = "1",
day = "1",
language = "English",
volume = "50",
pages = "114--118",
journal = "International Journal of Hematology",
issn = "0925-5710",
publisher = "Springer Japan",
number = "1",

}

TY - JOUR

T1 - Inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia

T2 - A case report of 9-month-old infant

AU - Ohga, Shoichi

AU - Ishii, E.

AU - Fujioka, K.

AU - Ueda, K.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Recently, it has been reported that many patients with acute myelomonocytic leukemia showed rearrangements of chromosome 16 in leukemic cells and abnormal eosinophils in bone marrow. Among the reported cases, the youngest was a 14-month-old male infant. We report a 9-month-old female infant with acute myelomonocytic leukemia with leukemic cells having a pericentric inversion of chromosome 16, inv (16) (p13q22), and for whom abnormal immature eosinophils with basophilic granules were observed in the bone marrow. The patient achieved complete remission after several courses of combination chemotherapy, and neither abnormal marrow eosinophils nor chromosomal abnormalities have been founds after nine months.

AB - Recently, it has been reported that many patients with acute myelomonocytic leukemia showed rearrangements of chromosome 16 in leukemic cells and abnormal eosinophils in bone marrow. Among the reported cases, the youngest was a 14-month-old male infant. We report a 9-month-old female infant with acute myelomonocytic leukemia with leukemic cells having a pericentric inversion of chromosome 16, inv (16) (p13q22), and for whom abnormal immature eosinophils with basophilic granules were observed in the bone marrow. The patient achieved complete remission after several courses of combination chemotherapy, and neither abnormal marrow eosinophils nor chromosomal abnormalities have been founds after nine months.

UR - http://www.scopus.com/inward/record.url?scp=0023091446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023091446&partnerID=8YFLogxK

M3 - Article

C2 - 3473882

AN - SCOPUS:0023091446

VL - 50

SP - 114

EP - 118

JO - International Journal of Hematology

JF - International Journal of Hematology

SN - 0925-5710

IS - 1

ER -