Irciniasulfonic acid B, a novel taurine conjugated fatty acid derivative from a Japanese marine sponge, Ircinia sp.

Chisato Emura, Ryuichi Higuchi, Tomofumi Miyamoto

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Irciniasulfonic acid B (1) was obtained from a marine sponge, Ircinia sp., together with a known multi-drug resistance modulator irciniasulfonic acid (2). Spectroscopic and chemical analyses revealed structure consisting of common unsaturated fatty acids, a novel unsaturated branched fatty acid, and a taurine. Final separation of irciniasulfonic acid B (1) was achieved with its methylated derivatives. Irciniasulfonic acid B (1) reversed the multi-drug resistance in the same way as irciniasulfonic acid.

Original languageEnglish
Pages (from-to)5682-5685
Number of pages4
JournalTetrahedron
Volume62
Issue number24
DOIs
Publication statusPublished - Jun 12 2006

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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