Isolation and characterization of enterocin W, a novel two-peptide lantibiotic produced by Enterococcus faecalis NKR-4-1

Naruhiko Sawa, Pongtep Wilaipun, Seisuke Kinoshita, Takeshi Zendo, Vichien Leelawatcharamas, Jiro Nakayama, Kenji Sonomoto

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

Enterococcus faecalis NKR-4-1 isolated from pla-ra produces a novel two-peptide lantibiotic, termed enterocin W, comprising Wα and Wβ. The structure of enterocin W exhibited similarity with that of plantaricin W. The two peptides acted synergistically, and their order of binding to the cell membrane was important for their inhibitory activity.

Original languageEnglish
Pages (from-to)900-903
Number of pages4
JournalApplied and environmental microbiology
Volume78
Issue number3
DOIs
Publication statusPublished - Feb 2012

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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