Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii

Nagy Morsy, Shigeru Matsuoka, Toshihiro Houdai, Nobuaki Matsumori, Seiji Adachi, Michio Murata, Takashi Iwashita, Tsuyoshi Fujita

Research output: Contribution to journalArticlepeer-review

62 Citations (Scopus)

Abstract

A new member of amphidinols (AM7) possessing a polyene-polyhydroxyl structure with the shortest carbon backbone and sulfate ester was isolated from the cultured dinoflagellate, Amphidinium klebsii. AM7 showed hemolytic and antifungal activities. The structure was elucidated on the basis of 2D NMR data in combination with CID MS/MS experiments.

Original languageEnglish
Pages (from-to)8606-8610
Number of pages5
JournalTetrahedron
Volume61
Issue number36
DOIs
Publication statusPublished - Sep 5 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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